Imaging and Focal Therapy of Early Prostate Cancer

  • Thomas J. Polascik

Part of the Current Clinical Urology book series (CCU)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Scientific Foundation for the Focal Therapy Concept

    1. Front Matter
      Pages 1-1
    2. Joseph A. Graversen, Jaime Landman
      Pages 3-15
    3. Hendrik Van Poppel, Steven Joniau
      Pages 37-52
    4. Thomas J. Polascik, Arnauld Villers, Thomas M. Wheeler, David G. Bostwick, Rodolfo Montironi, Pierre Nevoux et al.
      Pages 53-71
    5. Markos Karavitakis, Mark Emberton, Hashim Uddin Ahmed
      Pages 73-80
    6. G. H. J. M. Leyten, J. A. Schalken
      Pages 81-94
  3. Advances in Prostate Biopsy Technique

    1. Front Matter
      Pages 95-95
    2. Ryan Berglund, J. Stephen Jones
      Pages 97-101
    3. Samuel Clark Berngard, Kyle O. Rove, Jens Rassweiler, Oliver Kalthoff, Marcel Hruz, E. David Crawford
      Pages 103-117
    4. Osamu Ukimura, André Luis de Castro Abreu
      Pages 119-132
    5. Arnauld Villers, Adil Ouzzane
      Pages 133-140
  4. Functional and Molecular Imaging

    1. Front Matter
      Pages 153-153
    2. M. Smeenge, M. Mischi, M. P. Laguna, J. J. M. C. H. de la Rosette, H. Wijkstra
      Pages 155-164
    3. Stephen Rosenzweig, Liang Zhai, Kathryn R. Nightingale
      Pages 165-172
    4. Sadhna Verma, Michael A. S. Lamba, Daniel B. Vigneron, Adam Jung, John Kurhanewicz
      Pages 173-202
    5. Nazila Kamaly, Archana Swami, Ryan Wagner, Omid Cameron Farokhzad
      Pages 203-217
    6. Baris Turkbey, Peter L. Choyke
      Pages 219-234
  5. Focal Therapy Nomenclature and Patient Selection

    1. Front Matter
      Pages 235-235
    2. Vladimir Mouraviev, Thomas J. Polascik
      Pages 245-253
    3. Louise Dickinson, Hashim Uddin Ahmed, Mark Emberton
      Pages 255-269
  6. Novel Thermoablation Technologies for Focal Therapy

    1. Front Matter
      Pages 271-271
    2. Satoru Muto, Shigeo Horie
      Pages 273-282
    3. Caroline M. Moore, Mark Emberton
      Pages 283-295
    4. Uri Lindner, John Trachtenberg
      Pages 297-307
    5. William W. Roberts
      Pages 331-343
    6. David A. Levy, J. Stephen Jones
      Pages 345-353
    7. John M. Baust, Kimberly Santucci, Andrew A. Gage, Anthony Robilotto
      Pages 355-366
  7. Post-treatment Follow-Up and Future Directions

    1. Front Matter
      Pages 367-367
    2. David S. Finley, Arie S. Belldegrun
      Pages 369-382
    3. Thomas J. Polascik, Vladimir Mouraviev
      Pages 383-388
  8. John M. Baust, Kimberly Santucci, Andrew A. Gage, Anthony Robilotto, John G. Baust
    Pages E1-E1
  9. Back Matter
    Pages 389-396

About this book


Imaging and Focal Therapy of Early Prostate Cancer evaluates the scientific evidence for the evolving trend to treat low to intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablation, among others, are discussed in regard to their strengths and limitations as a therapeutic modality. Emphasis is placed on tumor stage shift towards early stage disease with an increase in unilateral versus bilateral cancers validated by final pathology assessment of large prostatectomy series. Current and new approaches to image cancer foci within the prostate (3-Dimensional contrast-enhanced transrectal ultrasonography, multiparametric magnetic resonance image with spectroscopy,  ETC) are presented along with biopsy techniques to map prostate cancer. Patient selection, treatment strategy, outcomes and safety concerns that may provide acceptable cancer control and improved quality of life for patients are all covered in detail.
Written by experts in the field and lavishly illustrated with detailed line-art and photographs, Imaging and Focal Therapy of Early Prostate Cancer is a resourceful volume beneficial to practitioners specializing in the treatment and management of prostate cancer.


Constrast enhanced ultrasonography Elastography Spatial focality Stereotactic image guided biopsy Thermoblation

Editors and affiliations

  • Thomas J. Polascik
    • 1
  1. 1., Department of SurgeryDuke Cancer InstituteDurhamUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2013
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-62703-181-3
  • Online ISBN 978-1-62703-182-0
  • Buy this book on publisher's site
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Health & Hospitals