Ghrelin in Health and Disease

  • Roy G. Smith
  • Michael O. Thorner

Part of the Contemporary Endocrinology book series (COE, volume 10)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Cyril Y. Bowers, G. A. Reynolds, Johannes D. Veldhuis
    Pages 1-35
  3. Masayasu Kojima, Kenji Kangawa
    Pages 37-49
  4. Luisa María Seoane, Ana Belen Crujeiras, Omar Al-Massadi, Felipe F. Casanueva
    Pages 73-89
  5. Miski Scerif, Blerina Kola, Márta Korbonits
    Pages 91-110
  6. Pablo J. Enriori, Zane B. Andrews, Michael Alexander Cowley
    Pages 111-130
  7. Henriette Kirchner, Matthias Tschöp, Jenny Tong
    Pages 131-147
  8. Éva Szentirmai, Levente Kapás
    Pages 149-170
  9. Elisabet Jerlhag, Emil Egecioglu, Jörgen Engel, Suzanne L. Dickson
    Pages 181-197
  10. Ralf Nass, Michael O. Thorner
    Pages 199-211
  11. Damien Ashby, Peter Choi, Stephen Bloom
    Pages 231-256
  12. Sachiko Miyake, Takashi Yamamura
    Pages 257-266
  13. S. J. C. M. M. Neggers, Riccarda Granata, Ezio Ghigo, Aart J. van der Lely
    Pages 267-275
  14. Back Matter
    Pages 285-290

About this book


Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.

Editors and affiliations

  • Roy G. Smith
    • 1
  • Michael O. Thorner
    • 2
  1. 1., Department of Metabolism and AgingThe Scripps Research Institute FloridaJupiterUSA
  2. 2., Department of MedicineUniversity of VirginiaCharlottesvilleUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine
  • Print ISBN 978-1-61779-902-0
  • Online ISBN 978-1-61779-903-7
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology