Hepatic Encephalopathy

  • Kevin D. Mullen
  • Ravi K. Prakash

Part of the Clinical Gastroenterology book series (CG)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Pathogenesis

    1. Front Matter
      Pages 5-5
    2. Shabnam S. Shabbir, Amit Singh Seyan, Debbie Lindsay Shawcross
      Pages 35-45
    3. Arumugam R. Jayakumar, Michael D. Norenberg
      Pages 47-70
  3. Diagnosis

    1. Front Matter
      Pages 95-95
    2. Karin Weissenborn
      Pages 97-102
    3. Jennifer Y. Montgomery, Jasmohan S. Bajaj
      Pages 103-112
    4. Rita García-Martínez, Juan Córdoba
      Pages 123-137
  4. Treatment

    1. Front Matter
      Pages 139-139
    2. Praveen Sharma, Shiv Kumar Sarin
      Pages 141-158
    3. Kevin D. Mullen, Ravi K. Prakash
      Pages 159-164
    4. Maria Jover-Cobos, Nathan A. Davies, Yalda Sharifi, Rajiv Jalan
      Pages 165-174
  5. Special Topics

    1. Front Matter
      Pages 175-175
    2. Sara Montagnese
      Pages 177-186
    3. Matthew R. Kappus, Jasmohan S. Bajaj
      Pages 187-197
    4. Manuela Merli, Michela Giusto, Oliviero Riggio
      Pages 199-209
    5. Jillian Kallman Price, Zobair M. Younossi
      Pages 221-231
    6. Dileep K. Atluri, Kevin D. Mullen
      Pages 233-239
    7. Kevin D. Mullen, Ravi K. Prakash
      Pages 241-243
  6. Back Matter
    Pages 245-250

About this book


Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic.


            Hepatic Encephalopathy provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists, and general practitioners who treat patients with hepatic encephalopathy.



brain edema chronic liver failure covert hepatic encephalopathy pathogenesis pathophysiology

Editors and affiliations

  • Kevin D. Mullen
    • 1
  • Ravi K. Prakash
    • 2
  1. 1., Division of GastroenterologyMetroHealth Medical CenterClevelandUSA
  2. 2., Division of GastroenterologyMetroHealth Medical CenterClevelandUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-61779-835-1
  • Online ISBN 978-1-61779-836-8
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology