Cytoskeleton and Human Disease

  • Maria Kavallaris

Table of contents

  1. Front Matter
    Pages 1-1
  2. Basics of the Cytoskeleton

    1. Front Matter
      Pages 1-1
    2. Vera Dugina, Richard Arnoldi, Paul A. Janmey, Christine Chaponnier
      Pages 3-28
    3. Pavel Dráber, Eduarda Dráberová
      Pages 29-53
    4. Linda Wordeman
      Pages 55-72
    5. Omar A. Quintero, Judy E. Moore, Christopher M. Yengo
      Pages 73-100
  3. Actin and Disease

    1. Front Matter
      Pages 101-101
    2. Rhea Cornely, Thomas Grewal, Katharina Gaus
      Pages 103-121
    3. Anthony J. Kee, Edna C. Hardeman
      Pages 123-140
    4. Stephen P. Robertson, Philip B. Daniel
      Pages 141-158
    5. Alice Schofield, Ora Bernard
      Pages 159-168
    6. Matías Morín, Fernando Mayo, Felipe Moreno, Miguel A. Moreno-Pelayo
      Pages 169-180
    7. Teresa Bonello, Jason Coombes, Galina Schevzov, Peter Gunning, Justine Stehn
      Pages 181-200
  4. Microtubules and Disease

    1. Front Matter
      Pages 201-201
    2. April L. Risinger, Susan L. Mooberry
      Pages 203-221
    3. Joshua A. McCarroll, Maria Kavallaris
      Pages 223-240
    4. Suzan K. Chao, Chia-Ping H. Yang, Susan Band Horwitz
      Pages 241-257
    5. Dominic Chi Hiung Ng, Frances Byrne
      Pages 259-284
    6. Garth F. Hall
      Pages 285-313
    7. Xavier H. Jaglin, Jamel Chelly, Nadia Bahi-Buisson
      Pages 315-341
  5. Intermediate Filaments and Disease

    1. Front Matter
      Pages 343-343
    2. Marie-Christine Lecomte
      Pages 345-374
    3. Nadir M. Maraldi, Giovanna Lattanzi
      Pages 375-409
    4. J. Scott Pattison, Jeffrey Robbins
      Pages 411-424
    5. Rodolphe Perrot, Jean-Pierre Julien
      Pages 425-448
  6. Back Matter
    Pages 434-434

About this book


The cytoskeleton is made up of a large variety of specialized proteins and is a highly dynamic system that is involved in the majority of key cellular events. It is now clear that the cytoskeleton is often associated, and has diverse roles in human disease.  Emerging understanding of the molecular and cellular events that drive cytoskeletal mediated disease including cancer, heart disease, myopathies, neurodegenerative diseases and skin disorders, are also helping shape targeted therapeutic approaches to treat these diseases.


Cytoskeleton and Human Disease Book Summary reviews the key components, mechanisms and clinical implications of cytoskeletal defects in disease. Contributed by leading investigators in their respective fields, the chapters include topics associated with the basics of the cytoskeleton, actin-associated disease states, microtubule-associated disease states and intermediate filament-associated disease states.


This authoritative volume is intended for a wide audience of clinicians, researchers and students with an interest in the application of biomedical research to the understanding and management of disease states associated with the cytoskeleton.


Cell Biology Cytoskeleton Disease Human Kavallaris

Editors and affiliations

  • Maria Kavallaris
    • 1
  1. 1.Australia for Medical Research, Iron Metabolism ProgramChildren's Cancer InstituteRandwickAustralia

Bibliographic information

Industry Sectors
Health & Hospitals