Quantitative Trait Loci (QTL)

Methods and Protocols

  • Scott A. Rifkin

Part of the Methods in Molecular Biology book series (MIMB, volume 871)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Setting Up Mapping Populations

    1. Front Matter
      Pages 1-1
    2. Rik Kooke, Erik Wijnker, Joost J. B. Keurentjes
      Pages 3-16
    3. Yuan-Ming Zhang
      Pages 17-29
    4. Maitreya J. Dunham
      Pages 41-54
    5. Matthew A. Cleveland, Nader Deeb
      Pages 55-71
  3. Identifying Quantitative Trait Loci

    1. Front Matter
      Pages 73-73
    2. Xiao-Lin Wu, Zhi-Liang Hu
      Pages 145-171
  4. Extending the Power of Quantitative Trait Locus Analysis

    1. Front Matter
      Pages 173-173
    2. José M. Álvarez-Castro, Örjan Carlborg, Lars Rönnegård
      Pages 191-204
    3. Samprit Banerjee, Nengjun Yi
      Pages 205-225
    4. Kiranmoy Das, Zhongwen Huang, Jingyuan Liu, Guifang Fu, Jiahan Li, Yao Li et al.
      Pages 227-243
    5. Jiahan Li, Kiranmoy Das, Jingyuan Liu, Guifang Fu, Yao Li, Christian Tobias et al.
      Pages 245-261
  5. Case Studies

    1. Front Matter
      Pages 263-263
    2. Lun Li, Xianghua Zhang, Hongyu Zhao
      Pages 265-279
    3. Jürgen Gadau, Christof Pietsch, Leo W. Beukeboom
      Pages 313-328
  6. Back Matter
    Pages 329-331

About this book


Over the last two decades advances in genotyping technology, and the development of quantitative genetic analytical techniques have made it possible to dissect complex traits and link quantitative variation in traits to allelic variation on chromosomes or quantitative trait loci (QTLs). In Quantitative Trait Loci (QTLs):Methods and Protocols, expert researchers in the field detail methods and techniques that focus on specific components of the entire process of quantitative train loci experiments. These include methods and techniques for the mapping populations, identifying quantitative trait loci, extending the power of quantitative trait locus analysis, and case studies. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.


Thorough and intuitive, Quantitative Trait Loci (QTLs):Methods and Protocols aids scientists in the further study of the links between phenotypic and genotypic variation in fields from medicine to agriculture, from molecular biology to evolution to ecology.


Mendelian traits agriculture allelic variation ecology genotypic variation human disease medicine molecular biology phenotypic variation quantitative trait loci

Editors and affiliations

  • Scott A. Rifkin
    • 1
  1. 1.University of California, San DiegoLa JollaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-784-2
  • Online ISBN 978-1-61779-785-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals