Chromatin Remodeling

Methods and Protocols

  • Randall H. Morse

Part of the Methods in Molecular Biology book series (MIMB, volume 833)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Juan Jose Infante, G. Lynn Law, Elton T. Young
    Pages 63-87
  3. Ashwin Unnikrishnan, Bungo Akiyoshi, Sue Biggins, Toshio Tsukiyama
    Pages 115-123
  4. Russell P. Darst, Carolina E. Pardo, Santhi Pondugula, Vamsi K. Gangaraju, Nancy H. Nabilsi, Blaine Bartholomew et al.
    Pages 125-141
  5. Stephanie Byrum, Sherri K. Smart, Signe Larson, Alan J. Tackett
    Pages 143-152
  6. Florian Mueller, Tatiana S. Karpova, Davide Mazza, James G. McNally
    Pages 153-176
  7. Mala Singh, Amol Ranjan, Krishan Mohan Rai, Sunil Kumar Singh, Verandra Kumar, Ila Trivedi et al.
    Pages 201-223
  8. Ila Trivedi, Krishan Mohan Rai, Sunil Kumar Singh, Verandra Kumar, Mala Singh, Amol Ranjan et al.
    Pages 225-236
  9. Miyong Yun, Chun Ruan, Jae-Wan Huh, Bing Li
    Pages 237-253
  10. Christian J. Wippo, Philipp Korber
    Pages 271-287
  11. Heather J. Szerlong, Jeffrey C. Hansen
    Pages 289-310
  12. Hillel I. Sims, Chuong D. Pham, Gavin R. Schnitzler
    Pages 311-336
  13. Kyle Tsui, Tanja Durbic, Marinella Gebbia, Corey Nislow
    Pages 389-411
  14. Sheila S. Teves, Steven Henikoff
    Pages 421-432
  15. Songjoon Baek, Myong-Hee Sung, Gordon L. Hager
    Pages 433-441
  16. Back Matter
    Pages 451-453

About this book


Chromatin is of central importance to gene regulation in eukaryotes.  Reflecting this singular role for chromatin, numerous approaches have evolved in the laboratory over the past three decades to study chromatin structure and its alterations. Methods of investigating chromatin remodeling, whether in changes in nucleosome structure or position with respect to the incorporated DNA or in histone modifications, have progressed rapidly over the recent years.  In Chromatin Remodeling: Methods and Protocols, expert researchers contribute chapters which include methods for investigating chromatin remodeling in vitro and in vivo, in yeast, plants, and mammalian cells, and at local and global levels.  Both gene-specific and genome-wide approaches are covered, and in recognition of the increasing prevalence of the latter type of study, the final two chapters focus on bioinformatic/computational approaches to analyzing genome-wide data on chromatin structure. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.


Comprehensive and essential, Chromatin Remodeling: Methods and Protocols serves as a key source of clear techniques as well as a collection of chapters that can inspire future techniques in this vital field of study.


Chromatin Developmental biology Epigenetics & epigenomics Gene regulation Genome-wide data Histones Nucleosomes Transcription

Editors and affiliations

  • Randall H. Morse
    • 1
  1. 1., Wadsworth CenterNew York State Department of HealthAlbanyUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-476-6
  • Online ISBN 978-1-61779-477-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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