Next Generation Microarray Bioinformatics

Methods and Protocols

  • Junbai Wang
  • Aik Choon Tan
  • Tianhai Tian

Part of the Methods in Molecular Biology book series (MIMB, volume 802)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction and Resources for Microarray Bioinformatics

    1. Front Matter
      Pages 1-1
    2. Alexander J. Trachtenberg, Jae-Hyung Robert, Azza E. Abdalla, Andrew Fraser, Steven Y. He, Jessica N. Lacy et al.
      Pages 3-17
    3. Masaaki Kotera, Mika Hirakawa, Toshiaki Tokimatsu, Susumu Goto, Minoru Kanehisa
      Pages 19-39
  3. Microarray Data Analysis (Top-Down Approach)

    1. Front Matter
      Pages 55-55
    2. Peter Van Loo, Gro Nilsen, Silje H. Nordgard, Hans Kristian Moen Vollan, Anne-Lise Børresen-Dale, Vessela N. Kristensen et al.
      Pages 57-72
    3. Jia Meng, Yufei Huang
      Pages 87-100
    4. Gang Feng, Pamela Shaw, Steven T. Rosen, Simon M. Lin, Warren A. Kibbe
      Pages 101-112
    5. Fang Liu, Winston P. Kuo, Tor-Kristian Jenssen, Eivind Hovig
      Pages 141-155
    6. Levi Waldron, Hilary A. Coller, Curtis Huttenhower
      Pages 157-182
  4. Microarray Bioinformatics in Systems Biology (Bottom-Up Approach)

  5. Next Generation Sequencing Data Analysis

    1. Front Matter
      Pages 247-247
    2. Andreas Gogol-Döring, Wei Chen
      Pages 249-257
    3. Daniel Ramsköld, Ersen Kavak, Rickard Sandberg
      Pages 259-274
    4. Brian A. Kennedy, Xun Lan, Tim H.-M. Huang, Peggy J. Farnham, Victor X. Jin
      Pages 323-334
  6. Emerging Applications of Microarray and Next Generation Sequencing

  7. Back Matter
    Pages 399-401

About this book


 Recent improvements in the efficiency, quality, and cost of genome-wide sequencing have prompted biologists and biomedical researchers to move away from microarray-based technology to ultra high-throughput, massively parallel genomic sequencing (Next Generation Sequencing, NGS) technology. In Next Generation Microarray Bioinformatics: Methods and Protocols, expert researchers in the field provide techniques to bring together current computational and statistical methods to analyze and interpreting both microarray and NGS data. These methods and techniques include resources for microarray bioinformatics, microarray data analysis, microarray bioinformatics in systems biology, next generation sequencing data analysis, and emerging applications of microarray and next generation sequencing. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.


Authoritative and practical, Next Generation Microarray Bioinformatics: Methods and Protocols seeks to aid scientists in the further study of this crucially important research into the human DNA.


Bioinformatics ChIP-chip DNA Next Generation Sequencing, NGS genomic hybridization (aCGH) human genome project microRNA microarray single-nucleotide polymorphisms (SNPs)

Editors and affiliations

  • Junbai Wang
    • 1
  • Aik Choon Tan
    • 2
  • Tianhai Tian
    • 3
  1. 1.Norwegian Radium HospitalOslo University HospitalOsloNorway
  2. 2.School of MedicineUniversity of Colorado DenverAuroraUSA
  3. 3.School of Mathematics and StatisticsUniversity of GlasgowGlasgowUnited Kingdom

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-399-8
  • Online ISBN 978-1-61779-400-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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