Androgen Action

Methods and Protocols

  • Fahri Saatcioglu

Part of the Methods in Molecular Biology book series (MIMB, volume 776)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Reviews

    1. Front Matter
      Pages 1-1
    2. Diping Wang, Donald J. Tindall
      Pages 25-44
  3. Analysis of Androgens

    1. Front Matter
      Pages 45-45
    2. Clémentine Féau, Leggy A. Arnold, Aaron Kosinski, R. Kiplin Guy
      Pages 59-68
  4. Androgen Receptor Biology

    1. Front Matter
      Pages 69-69
    2. Harri Makkonen, Tiina Jääskeläinen, Miia M. Rytinki, Jorma J. Palvimo
      Pages 71-80
    3. Reinhilde De Bruyn, Rita Bollen, Frank Claessens
      Pages 81-93
    4. Helen Cheng, Eric Leblanc, Paul S. Rennie
      Pages 95-112
  5. Analysis of Androgen Receptor Modifications and Interactions

    1. Front Matter
      Pages 167-167
    2. Chenguang Wang, Michael Powell, Lifeng Tian, Richard G. Pestell
      Pages 169-181
    3. Miia M. Rytinki, Sanna Kaikkonen, Päivi Sutinen, Jorma J. Palvimo
      Pages 183-197
    4. Claudia Gerlach*, Daniela Roell*, Aria Baniahmad
      Pages 199-223
    5. Thomas Linke, Martin Scholten, Aria Baniahmad
      Pages 225-251
  6. Recent Advances in Studying Androgen Receptor Signalling

    1. Front Matter
      Pages 253-253

About this book

Introduction

Androgens play a critical role in the development and maintenance of the male reproductive system and affect important physiological processes and pathological conditions, including the homeostasis of the normal prostate and prostate cancer. Androgen Action: Methods and Protocols is designed to provide a tool box to study various phases of androgen action, from its entry to the cell to the phenotypic response that the cell mounts, with up-to-date techniques for biochemists, molecular biologists, cell biologists, geneticists, and pathologists. The volume opens with a brief review of the research history on androgen action and prostate carcinogenesis, followed by chapters that cover state-of-the-art methods to determine androgen levels in biological tissues and fluids, experimental procedures to study the various aspects of androgen receptor activity, and methodology to study salient examples of interactions between androgen signalling and other major signalling pathways in cells. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible, Androgen Action: Methods and Protocols provides a comprehensive overview of, and practical guidance on, the diverse methodologies that are propelling androgen action research forward, both for normal physiology as well as in disease states.

Keywords

androgen receptor carcinogenesis cellular signaling pathways phenotypic response prostate cancer reporter gene assays

Editors and affiliations

  • Fahri Saatcioglu
    • 1
  1. 1.Dept. Molecular BiosciencesUniversity of OsloOsloNorway

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-243-4
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-242-7
  • Online ISBN 978-1-61779-243-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book
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