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© 2011

The Opiate Receptors

  • Gavril W. Pasternak
  • 1. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years

  • Covers a wide variety of topics relating to opioid drugs and mu receptors, delta receptors, and kappa opioid receptors

  • 3. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor

Book

Part of the The Receptors book series (REC)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Solomon H. Snyder
    Pages 1-6
  3. W. R. Martin
    Pages 7-21
  4. Brian M. Cox
    Pages 23-57
  5. Gavril W. Pasternak
    Pages 59-91
  6. Iryna Berezniuk, Lloyd D. Fricker
    Pages 93-120
  7. Ying-Xian Pan, Gavril W. Pasternak
    Pages 121-160
  8. Wendy Walwyn, Fatima Macho Sánchez-Simon, Raquel Rodriguez, Christopher J. Evans
    Pages 161-179
  9. Howard L. Fields
    Pages 239-264
  10. Julia C. Lemos, Charles Chavkin
    Pages 265-305
  11. Edita Navratilova, Victor J. Hruby, Frank Porreca
    Pages 307-339
  12. Michael A. Ansonoff, Ting Wen, John E. Pintar
    Pages 341-388
  13. Mark von Zastrow
    Pages 389-405
  14. Raphael Rozenfeld, Ivone Gomes, Lakshmi A. Devi
    Pages 407-437
  15. Charles E. Inturrisi, Ann M. Gregus
    Pages 439-455
  16. Jörn Lötsch, Jeffrey S. Mogil
    Pages 457-497
  17. Back Matter
    Pages 499-516

About this book

Introduction

In 1988, Gavril W. Pasternak published the first edition of this seminal text. It was a lucid account of the latest knowledge on opiate receptors and related receptor subtypes, a then controversial field, providing an integrated approach correlating the biochemical, physiological, and pharmacological aspects of opiate reaction. Fully revised and expanded, The Opiate Receptors, 2nd edition presents all the advances made in the field in the past twenty years. It covers a wide variety of topics including, but not limited to, the following: pharmacology of opioid drugs; endogenous opioids; molecular biology of mu receptors; molecular biology of delta receptors; kappa opioid receptor gene and the regulatory mechanisms of its protein expression; opioid receptor signal transduction mechanisms; mu opioid receptor mediated analgesia and reward; kappa opioid receptor function; delta opioid receptor function; genetics of opioid receptor functions in mice; opioid receptor trafficking; opioid receptor dimerization; molecular modulation of in vivo tolerance; and genetics of opioid actions. Written by leading international researchers in the field, this new edition is as groundbreaking and vital as its predecessor.

Editors and affiliations

  • Gavril W. Pasternak
    • 1
  1. 1., Sloan-Kettering InstituteMemorial Sloan-Kettering Cancer CenterNew YorkUSA

About the editors

In 1988, Gavril W. Pasternak published the first edition of The Opiate Receptors. Dr. Pasternak is affiliated with the Molecular Pharmacology & Chemistry department at the Sloan-Kettering Institute (Memorial Sloan-Kettering Cancer Center).

Bibliographic information

  • Book Title The Opiate Receptors
  • Editors Gavril W. Pasternak
  • Series Title The Receptors
  • Series Abbreviated Title The Receptors
  • DOI https://doi.org/10.1007/978-1-60761-993-2
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-1-60761-992-5
  • Softcover ISBN 978-1-61779-721-7
  • eBook ISBN 978-1-60761-993-2
  • Series ISSN 1048-6909
  • Series E-ISSN 2524-6488
  • Edition Number 2
  • Number of Pages XII, 516
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Neurosciences
  • Buy this book on publisher's site
Industry Sectors
Biomedicine
Biotechnology
Health & Hospitals
Pharma

Reviews

From the reviews of the second edition:

“It is intended as a review and reference resource on topics of interest to scientists working in the opioid receptor field. … would be most appropriate for midlevel graduate students and higher level researchers … . The book offers a detailed overview and review of 14 different aspects of opioid receptor science … . an excellent source for a graduate level course on opioid pharmacology, or would serve well as a current reference point on timely issues in this field of research.” (Kenneth E. McCarson, Doody’s Review Service, June, 2011)

“The major goal of this second edition of The Opiate Receptors is to provide insight into the molecular and classical pharmacology of opiates and opioid peptides and to translate this into pharmacological actions. Gavril Pasternak … does a masterful job of bringing all of this together. … This book will be a valuable resource for scientists working in the opiate field and for clinicians who are interested in the pharmacological actions of these agents.” (Dwight Moulin, Canadian Journal of Neurological Sciences, March, 2012)