Data Mining in Proteomics

From Standards to Applications

  • Michael Hamacher
  • Martin Eisenacher
  • Christian Stephan

Part of the Methods in Molecular Biology book series (MIMB, volume 696)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Data Generation and Result Finding

    1. Front Matter
      Pages 1-1
    2. Caroline May, Frederic Brosseron, Piotr Chartowski, Cornelia Schumbrutzki, Bodo Schoenebeck, Katrin Marcus
      Pages 3-26
    3. Daniel Chamrad, Gerhard Körting, Martin Blüggel
      Pages 27-40
    4. Christoph Schaab
      Pages 41-57
  3. Databases

    1. Front Matter
      Pages 59-59
    2. Jari Häkkinen, Fredrik Levander
      Pages 79-92
    3. Juan Antonio Vizcaíno, Florian Reisinger, Richard Côté, Lennart Martens
      Pages 93-105
    4. Bryan E. Smith, James A. Hill, Mark A. Gjukich, Philip C. Andrews
      Pages 123-145
  4. Standards

    1. Front Matter
      Pages 147-147
    2. Sandra Orchard, Henning Hermjakob
      Pages 149-160
    3. Andreas Römpp, Thorsten Schramm, Alfons Hester, Ivo Klinkert, Jean-Pierre Both, Ron M. A. Heeren et al.
      Pages 205-224
  5. Processing and Interpretation of Data

    1. Front Matter
      Pages 233-233
    2. Michael Hamacher, Bernd Gröttrup, Martin Eisenacher, Katrin Marcus, Young Mok Park, Helmut E. Meyer et al.
      Pages 235-246
    3. Andreas Schüler, Erich Bornberg-Bauer
      Pages 273-289
    4. Michael Kohl, Sebastian Wiese, Bettina Warscheid
      Pages 291-303
    5. Axel Kowald, Sebastian Schmeier
      Pages 305-318
    6. Sarah R. Hart, King Wai Lau, Simon J. Gaskell, Simon J. Hubbard
      Pages 327-337
  6. Tools

    1. Front Matter
      Pages 339-339
    2. Chris Bauer, Rainer Cramer, Johannes Schuchhardt
      Pages 341-352
    3. Andreas Bertsch, Clemens Gröpl, Knut Reinert, Oliver Kohlbacher
      Pages 353-367
    4. Patricia M. Palagi, Markus Müller, Daniel Walther, Frédérique Lisacek
      Pages 369-377
  7. Modelling and Systems Biology

    1. Front Matter
      Pages 379-379
    2. Thomas Millat, Olaf Wolkenhauer, Ralf-Jörg Fischer, Hubert Bahl
      Pages 429-447
  8. Back Matter
    Pages 449-461

About this book


Through the rapid development of proteomics methods and technologies, an enormous amount of data was created, leading to a wide-spread rethinking of strategy design and data interpretation. In Data Mining in Proteomics: From Standards to Applications, experts in the field present these new insights within the proteomics community, taking the historical evolution as well as the most important international standardization projects into account. Along with basic and sophisticated overviews of proteomics technologies, standard data formats, and databases, the volume features chapters on data interpretation strategies including statistics, spectra interpretation, and analysis environments as well as specialized tasks such as data annotation, peak picking, phosphoproteomics, spectrum libraries, LC/MS imaging, and splice isoforms. As a part of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and cutting-edge, Data Mining in Proteomics: From Standards to Applications is a well-balanced compendium for beginners and experts, offering a broad scope of data mining topics but always focusing on the current state-of-the-art and beyond.


Data generation & handling Data interpretation International standardization projects Laboratory databases Modeling Public repositories Spectra interpretation Statistics Visualization

Editors and affiliations

  • Michael Hamacher
    • 1
  • Martin Eisenacher
    • 2
  • Christian Stephan
    • 3
  1. 1.Lead Discovery Center GmbHDortmundGermany
  2. 2.Medizinisches Proteom-CenterRuhr-Universität BochumBochumGermany
  3. 3.Medizinisches Proteom-CenterRuhr-Universität BochumBochumGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-986-4
  • Online ISBN 978-1-60761-987-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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