Tissue Microarrays

Methods and Protocols

  • Ronald Simon

Part of the Methods in Molecular Biology book series (MIMB, volume 664)

Table of contents

  1. Front Matter
    Pages i-x
  2. Pierre Tennstedt, Guido Sauter
    Pages 17-26
  3. Guido Sauter
    Pages 27-35
  4. Martina Mirlacher, Ronald Simon
    Pages 37-44
  5. Thai Hong Tran, Justin Lin, Ashley Brooke Sjolund, Fransiscus Eri Utama, Hallgeir Rui
    Pages 45-52
  6. Andréa Rodrigues Cordovil Pires, Simone Rabello de Souza
    Pages 53-61
  7. William J. Howat, Susan J. Wilson
    Pages 63-72
  8. Marlena Schoenberg Fejzo, Dennis J. Slamon
    Pages 73-80
  9. Zhongting Hu, Elbert Chang, Melissa Hodeib
    Pages 81-91
  10. Shuchun Zhao, Yasodha Natkunam
    Pages 93-101
  11. Milton W. Datta, André A. Kajdacsy-Balla
    Pages 103-111
  12. Ronald Simon, Martina Mirlacher, Guido Sauter
    Pages 113-126
  13. Anne Kallioniemi
    Pages 127-134
  14. Marisa Dolled-Filhart, Mark Gustavson, Robert L. Camp, David L. Rimm, John L. Tonkinson, Jason Christiansen
    Pages 151-162
  15. Tibor Krenacs, Levente Ficsor, Sebestyen Viktor Varga, Vivien Angeli, Bela Molnar
    Pages 163-175
  16. Thorsten Schlomm, Felix KH Chun, Andreas Erbersdobler
    Pages 177-189
  17. Back Matter
    Pages 191-193

About this book


Today’s tissue microarray (TMA) method presents as a modern high-tech technology, one which allows for the linking of clinical data to the tissues that are combined on one slide. In Tissue Microarrays: Methods and Protocols, expert researchers explore the current world of TMA making and TMA applications, providing insight into the inherent and complex aspects of the most popular assays used for in-situ tissue analysis. Chapters examine the range of TMA techniques that allow for a large number of tissues to be included in one TMA, preserve the integrity of donor tissue blocks, and present a highly organized array pattern that allows for the reliable allocation of clinical data to individual tissue spots. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Contemporary and ground-breaking, Tissue Microarrays: Methods and Protocols serves as an essential handbook for pathologists, molecular biologists, researchers in the life sciences, as well as physicians, a reflection of the various applications of current TMA technology.


DNA Microarray Prevalence array Prognosis array Progression array RNA TMA technology genes hybridization molecular biology

Editors and affiliations

  • Ronald Simon
    • 1
  1. 1.Institute of PathologyUniversity Medical Ctr Hamburg-EppendorfHamburgGermany

Bibliographic information

  • DOI
  • Copyright Information Springer Science + Business Media, LLC 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-805-8
  • Online ISBN 978-1-60761-806-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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