Systems Biology in Drug Discovery and Development

Methods and Protocols

  • Qing Yan

Part of the Methods in Molecular Biology book series (MIMB, volume 662)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Methodologies of Systems Biology in Drug Discovery and Development

    1. Front Matter
      Pages 1-1
    2. Bulbul Chakravarti, Buddhadeb Mallik, Deb N. Chakravarti
      Pages 3-28
    3. André Schrattenholz, Karlfried Groebe, Vukic Soskic
      Pages 29-58
    4. Najl V. Valeyev, Declan G. Bates, Yoshinori Umezawa, Antonina N. Gizatullina, Nikolay V. Kotov
      Pages 79-95
    5. Ravishankar R. Vallabhajosyula, Alpan Raval
      Pages 97-120
    6. Marco Grzegorczyk
      Pages 121-147
  3. Systems Biology Methods for Disease Treatment and Translational Medicine

    1. Front Matter
      Pages 179-179
    2. Yoram Vodovotz, Gary An
      Pages 181-201
    3. Yuri Nikolsky, Robert Kleemann
      Pages 221-243
    4. Dana Faratian, James L. Bown, V. Anne Smith, Simon P. Langdon, David J. Harrison
      Pages 245-263
    5. Vasileios C. Kyttaris
      Pages 265-283
    6. Firas H. Kobeissy, Shankar Sadasivan, Melinda Buchanan, Zhiqun Zhang, Mark S. Gold, Kevin K. W. Wang
      Pages 303-316
    7. Zhiqun Zhang, Stephen F. Larner, Firas Kobeissy, Ronald L. Hayes, Kevin K. W. Wang
      Pages 317-329
  4. Erratum

    1. Dana Faratian, James L. Bown, V. Anne Smith, Simon P. Langdon, David J. Harrison
      Pages E1-E1
  5. Back Matter
    Pages 331-337

About this book


Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine.


Disease prevention and health promotion Holistic techniques Individualized therapeutics Personalized medicine Pharmaceuticals Translation Translational medicine amphetamine bioinformatics molecular biology physiology

Editors and affiliations

  • Qing Yan
    • 1
  1. 1.PharmTaoSanta ClaraUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-799-0
  • Online ISBN 978-1-60761-800-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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