Stem Cells for Myocardial Regeneration

Methods and Protocols

  • Randall J.┬áLee

Part of the Methods in Molecular Biology book series (MIMB, volume 660)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Isolation and Characterization of Cells for Myocardial Regeneration

  3. Isolation and Characterization of Cells for Myocardial Regeneration

    1. Front Matter
      Pages 7-7
    2. Nicholas Greco, Mary J. Laughlin
      Pages 29-52
    3. Otmar Pfister, Angelos Oikonomopoulos, Konstantina-Ioanna Sereti, Ronglih Liao
      Pages 53-63
    4. Andrew J. Boyle, Ian K. McNiece, Joshua M. Hare
      Pages 65-84
    5. Gil Arbel, Oren Caspi, Irit Huber, Amira Gepstein, Michal Weiler-Sagie, Lior Gepstein
      Pages 85-95
  4. Animal Models for Assessing Stem Cells for Myocardial Regeneration

  5. Histological Assessment of Myocardial Regeneration

    1. Front Matter
      Pages 123-123
    2. Naima Carter-Monroe, Elena Ladich, Renu Virmani, Frank D. Kolodgie
      Pages 125-148
  6. Measures of Cell Trafficking

    1. Front Matter
      Pages 169-169
    2. Karim Sallam, Joseph C. Wu
      Pages 185-199
    3. Sunny S.-K. Chan, Ying-Zhang Shueh, Nirma Bustamante, Shih-Jung Tsai, Hua-Lin Wu, Jyh-Hong Chen et al.
      Pages 201-211
  7. Electrophysiology

    1. Front Matter
      Pages 213-213
    2. Seth Weinberg, Elizabeth A. Lipke, Leslie Tung
      Pages 215-237
    3. Chunhua Ding, Thomas H. Everett IV
      Pages 239-252
  8. Biomaterials

    1. Front Matter
      Pages 253-253
    2. Karen L. Christman, Heather D. Maynard
      Pages 255-263
  9. Back Matter
    Pages 265-267

About this book


There is currently a great deal of enthusiasm surrounding organ regeneration, which mainly comes from the potential pleuripotency of stem cells to differentiate into various tissue types. In Stem Cells for Myocardial Regeneration: Methods and Protocols, expert researchers explore exciting new developments in the field of regenerative medicine, focusing both on the benefits of using stem cells in myocardial repair and regeneration and on the challenges associated with making this a mainstream therapy. Chapters consider the optimal cell type for myocardial repair, examine the developmental processes of the human heart in order to develop strategies for regeneration, consider ex-vivo optical mapping and in vivo electrophysiology studies, and investigate the effects of the extracellular matrix on stem cell renewal and differentiation. Composed in the highly successful Methods in Molecular Biology(tm) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Ground-breaking and current, Stem Cells for Myocardial Regeneration: Methods and Protocols, is an essential guide for scientists, translational investigators, and cardiologists alike, providing readers with a means to evaluate the efficacy and safety of adopting stem cells as the standard for myocardial regeneration.


Ex-vivo optical mapping Extracellular matrix In vivo electrophysiology studies Myocardial repair Translation Vivo cardiovascular cell biology molecular biology tissue

Editors and affiliations

  • Randall J.┬áLee
    • 1
  1. 1., Division of CardiologyUniversity of California, San FranciscoSan FranciscoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science + Business Media 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-704-4
  • Online ISBN 978-1-60761-705-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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