Photodynamic Therapy

Methods and Protocols

  • Charles J. Gomer

Part of the Methods in Molecular Biology book series (MIMB, volume 635)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Thomas J. Dougherty
    Pages 1-6
  3. Michael Dewaele, Tom Verfaillie, Wim Martinet, Patrizia Agostinis
    Pages 7-33
  4. David Kessel, Nancy L. Oleinick
    Pages 35-46
  5. Gurmit Singh, Omar Alqawi, Myrna Espiritu
    Pages 65-78
  6. Isabelle Coupienne, Jacques Piette, Sébastien Bontems
    Pages 79-95
  7. Kristian Berg, Anette Weyergang, Lina Prasmickaite, Anette Bonsted, Anders Høgset, Marie-Therese R. Strand et al.
    Pages 133-145
  8. Mladen Korbelik
    Pages 147-153
  9. Liyi Huang, Tianhong Dai, Michael R. Hamblin
    Pages 155-173
  10. Brian W. Pogue, Kimberley S. Samkoe, Summer L. Gibbs-Strauss, Scott C. Davis
    Pages 207-222
  11. Ravindra K. Pandey, Nadine S. James, Yihui Chen, Joseph Missert, Munawar Sajjad
    Pages 223-259
  12. Merrill A. Biel
    Pages 281-293
  13. Back Matter
    Pages 295-296

About this book


Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.


Cell death pathways Malignant and non-malignant diseases PDT research Photophysical methods Photosensitizers Signal transduction pathways Tumor treatment biology cancer cell cell death infection molecular biology signal transduction tumor

Editors and affiliations

  • Charles J. Gomer
    • 1
  1. 1.Keck School of Medicine, Children's Hospital Los AngelesUniversity of Southern CaliforniaLos AngelesUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-696-2
  • Online ISBN 978-1-60761-697-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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