© 2010

Suppressing the Mind

Anesthetic Modulation of Memory and Consciousness

  • Anthony Hudetz
  • Robert Pearce

Part of the Contemporary Clinical Neuroscience book series (CCNE)

Table of contents

  1. Front Matter
    Pages i-x
  2. Anthony Hudetz, Robert Pearce
    Pages 1-9
  3. Christopher J. Watson, Helen A. Baghdoyan, Ralph Lydic
    Pages 33-80
  4. Michael T. Alkire
    Pages 127-138
  5. Jamie Sleigh, Moira Steyn-Ross, Alistair Steyn-Ross, Logan Voss, Marcus Wilson
    Pages 139-160
  6. Robert A. Veselis, Kane O. Pryor
    Pages 215-243
  7. Back Matter
    Pages 242-252

About this book


By suppressing memory and consciousness - two components of the mind - anesthetics provide great relief to surgical patients and elicit wonder in clinicians and scientists. To-date we do not fully understand the mechanisms by which these effects are achieved. However, with recent advances in investigational technologies, ranging from molecular modeling and genetic manipulation to noninvasive functional brain imaging and computational approaches, substantial progress toward this goal has been made during the last decade.

Suppressing the Mind is a multidisciplinary collection of original results and authoritative overviews of the current state of knowledge of the problem written by investigators who are internationally known for their significant contribution to our current understanding of the mechanism of anesthesia. It attempts to bridge molecular, cellular, integrative and systems-level actions of anesthetics with respect to their effects on consciousness and memory. Through a better understanding of how anesthetics work, we hope to also uncover the neurobiological bases of some of the deepest mysteries of the human mind; how it self-reflectively knows, perceives and remembers.

This book should appeal to anesthesiologists, neurologists, psychologists, neuroscientists -- essentially anyone interested in anesthesia, consciousness, or memory. It provides insight into the current state of knowledge, and a perspective for future treatments of the subject as guided by novel hypotheses.


Nervous System anesthetic consciousness hudetz memory mind perception suppressing

Editors and affiliations

  • Anthony Hudetz
    • 1
  • Robert Pearce
    • 2
  1. 1.Dept. AnesthesiologyMedical College of WisconsinMilwaukeeU.S.A.
  2. 2.Dept. AnesthesiologyUniversity of Wisconsin-MadisonMadisonU.S.A.

Bibliographic information

  • Book Title Suppressing the Mind
  • Book Subtitle Anesthetic Modulation of Memory and Consciousness
  • Editors Anthony Hudetz
    Robert Pearce
  • Series Title Contemporary Clinical Neuroscience
  • Series Abbreviated Title Contemporary Clinical Neuroscience
  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Biomedical and Life Sciences Biomedical and Life Sciences (R0)
  • Hardcover ISBN 978-1-60761-463-0
  • Softcover ISBN 978-1-61779-678-4
  • eBook ISBN 978-1-60761-462-3
  • Edition Number 1
  • Number of Pages X, 252
  • Number of Illustrations 19 b/w illustrations, 19 illustrations in colour
  • Topics Anesthesiology
    Human Physiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Surgery & Anesthesiology


From the reviews:

“The editors present this book as the first book with a unified view of studies on anaesthetic modulation on both consciousness and memory to bridge molecular, cellular, integrative, and systems-level effects. … even the heavy technical information in the book is written in the style for a wider audience ― such as the JCS/Tucson toward-a-science-of-consciousness crowd.” (Bill Faw, Journal of Consciousness Studies, Vol. 18 (3-4), 2011)

“This is a compilation of 10 essays on the neuroscientific underpinnings of general anesthesia. … intended for anesthesia researchers, but the quality and the clarity of the writing make it accessible and interesting for anyone involved in clinical anesthesia care. … I found this book extremely enlightening. The authors have successfully presented the current state of scientific understanding in a way that appeals to clinical practitioners. I highly recommend this book to anyone who wants to gain a better understanding of how general anesthetics work.” (David B. Glick, Doody’s Review Service, May, 2010)