Immunotoxicity Testing

Methods and Protocols

  • Rodney R. Dietert

Part of the Methods in Molecular Biology™ book series (MIMB, volume 598)

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Michael I. Luster, G. Frank Gerberick
      Pages 3-13
  3. Overview and Health-Risk Considerations

    1. Front Matter
      Pages 16-16
    2. Irene S. Ludwig, Lydia M. Kwast, Daniëlle Fiechter, Raymond H. H. Pieters
      Pages 27-37
    3. Rodney R. Dietert, Janice M. Dietert, Jerrie Gavalchin
      Pages 39-51
    4. Dori R. Germolec, Rachel P. Frawley, Ellen Evans
      Pages 53-73
    5. John B. Barnett, Kathleen M. Brundage
      Pages 75-94
  4. Immunotoxicity and Host Resistance Models

    1. Front Matter
      Pages 96-96
    2. Florence G. Burleson, Gary R. Burleson
      Pages 97-108
    3. Wendy Jo Freebern
      Pages 109-117
    4. Sheung Ng, Kotaro Yoshida, Judith T. Zelikoff
      Pages 143-155
  5. Testing Protocols in Rodents and Other Laboratory Animals

    1. Front Matter
      Pages 158-158
    2. Lisa M. Plitnick, Danuta J. Herzyk
      Pages 159-171
    3. Kimber L. White, Deborah L. Musgrove, Ronnetta D. Brown
      Pages 173-184
    4. Rodney R. Dietert, Terry L. Bunn, Ji-Eun Lee
      Pages 185-194
    5. Gary R. Burleson, Florence G. Burleson, Rodney R. Dietert
      Pages 195-205
    6. Ian Kimber, Rebecca J. Dearman
      Pages 221-231
    7. Mitzi Nagarkatti, Sadiye Amcaoglu Rieder, Dilip Vakharia, Prakash S. Nagarkatti
      Pages 241-257
    8. Donghong Gao, David A. Lawrence
      Pages 259-281
    9. Emanuela Corsini, Robert V. House
      Pages 283-302
    10. Patrick B. Lappin
      Pages 303-321
    11. Stephanie Grote-Wessels, Werner Frings, Clifford A. Smith, Gerhard F. Weinbauer
      Pages 341-359
  6. Evaluation in Humans

    1. Front Matter
      Pages 362-362
    2. Robert V. House
      Pages 363-384
  7. Wildlife Testing

    1. Front Matter
      Pages 387-387
  8. In Vitro Alternatives

    1. Front Matter
      Pages 400-400
    2. D. P. K. Lankveld, H. Van Loveren, K. A. Baken, R. J. Vandebriel
      Pages 401-423
  9. Back Matter
    Pages 425-430

About this book


Recent critical advances in the field of immunotoxicology have led to incredible contributions to basic science, including crucial improvements in human risk assessment. In Immunotoxicity Testing: Methods and Protocols, expert researchers explore these changes, providing the reader with current, lab-ready procedures, along with the corresponding background information that is necessary to identify effective testing approaches for chemicals and drugs. Among the first volumes to meld consideration of immunotoxicity testing strategies with a comprehensive presentation of detailed laboratory protocols, chapters include a description of the evolution of immunotoxicity testing, a look at the importance of immunotoxicity testing for health risk reduction, and ideas concerning the future of the field. Composed in the highly successful Methods in Molecular Biology(tm) series format, most chapters contain a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips from the experts on troubleshooting and avoiding known pitfalls.

Comprehensive and innovative, Immunotoxicity Testing: Methods and Protocols is a critical, one-stop reference resource for the most important and commonly used laboratory protocols in immunotoxicology.


Alternative approaches Antigen Clinical evaluation approaches Developmental immunotoxicity Health risk reduction Host resistance models Immunotoxicology testing Laboratory

Editors and affiliations

  • Rodney R. Dietert
    • 1
  1. 1.College of Veterinary MedicineCornell UniversityIthacaU.S.A.

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-400-5
  • Online ISBN 978-1-60761-401-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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