Protein Networks and Pathway Analysis

  • Yuri Nikolsky
  • Julie Bryant

Part of the Methods in Molecular Biology book series (MIMB, volume 563)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Part I: Interactions

    1. Front Matter
      Pages 1-1
    2. Svetlana Bureeva, Svetlana Zvereva, Valentin Romanov, Tatiana Serebryiskaya
      Pages 75-95
  3. Part II: Analysis

    1. Front Matter
      Pages 97-97
    2. Charles A. Tilford, Nathan O. Siemers
      Pages 99-121
    3. Chad L. Myers, Camelia Chiriac, Olga G. Troyanskaya
      Pages 157-175
    4. Yuri Nikolsky, Eugene Kirillov, Roman Zuev, Eugene Rakhmatulin, Tatiana Nikolskaya
      Pages 177-196
    5. Ekaterina Mogilevskaya, Natalia Bagrova, Tatiana Plyusnina, Nail Gizzatkulov, Eugeniy Metelkin, Ekaterina Goryacheva et al.
      Pages 197-218
    6. Sarah Killcoyne, Gregory W. Carter, Jennifer Smith, John Boyle
      Pages 219-239
  4. Part III: Applications

    1. Front Matter
      Pages 273-273
    2. Ali Torkamani, Nicholas J. Schork
      Pages 289-301
    3. Giuseppe Russo, Antonio Giordano
      Pages 303-352
    4. Jerry M. Wright, Yuri Nikolsky, Tatiana Serebryiskaya, Diana R. Wetmore
      Pages 353-367
    5. Hong Fang, Stephen C. Harris, Zhenjiang Su, Minjun Chen, Feng Qian, Leming Shi et al.
      Pages 379-398
  5. Back Matter
    Pages 399-410

About this book


From the beginning of the OMICs biology era, science has been pursuing the reduction of the complex "genome-wide" assays in order to understand the essential biology that lies beneath it.  In Protein Networks and Pathway Analysis, expert practitioners present a compilation of methods of functional data analysis, often referred to as "systems biology," and its applications in drug discovery, medicine and basic disease research.  The volume is divided into three convenient sections, covering the elucidation of protein, compound and gene interactions, analytical tools, including networks, interactome and ontologies, and applications of functional analysis.  As a volume in the highly successful Methods in Molecular Biology™ series, this work provides detailed descriptions and hands-on implementation advice.


Authoritative and cutting-edge, Protein Networks and Pathway Analysis presents both "wet lab" experimental methods and computational tools in order to cover a broad spectrum of issues in this fascinating new field.


Biological ontology Computer methods Functional analysis Gene interactions Microarray Software tools Systems biology bioinformatics biology data analysis genes knowledge management miRNAs molecular biology transcription

Editors and affiliations

  • Yuri Nikolsky
    • 1
  • Julie Bryant
    • 2
  1. 1.GeneGo Inc.EncinitasU.S.A.
  2. 2.GeneGo Inc.EncinitasU.S.A.

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-174-5
  • Online ISBN 978-1-60761-175-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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