© 2012

Visual Dysfunction in Diabetes

The Science of Patient Impairment and Health Care

  • Joyce Tombran-Tink
  • Colin J. Barnstable
  • Thomas W. Gardner

Part of the Ophthalmology Research book series (OPHRES)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Living with Diabetic Retinopathy

    1. Front Matter
      Pages 1-1
  3. How Is Diabetic Retinopathy Detected?

  4. How does diabetes affect the Eye?

    1. Front Matter
      Pages 43-43
    2. Edoardo Midena
      Pages 45-51
    3. José Cunha-Vaz, Rui Bernardes, Conceição Lobo
      Pages 53-68
    4. Edoardo Midena, Stela Vujosevic
      Pages 69-103
    5. E. Aaron Runkle, Paul M. Titchenell, David A. Antonetti
      Pages 123-141
    6. Timothy S. Kern
      Pages 143-155
    7. Sampathkumar Rangasamy, Paul McGuire, Arup Das
      Pages 157-172
    8. Alistair J. Barber, William F. Robinson, Gregory R. Jackson
      Pages 189-209
    9. Zia A. Khan, Subrata Chakrabarti
      Pages 211-232
    10. Andreas Stahl, Ann Hellstrom, Chatarina Lofqvist, Lois Smith
      Pages 233-244
    11. Anne R. Murray, Jian-xing Ma
      Pages 245-259
    12. R. J. van Geest, E. J. Kuiper, I. Klaassen, C. J. F. van Noorden, R. O. Schlingemann
      Pages 261-285

About this book


An exciting contribution to the field, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement is designed with two overriding objectives: to help readers understand the impact of vision impairment in people living daily with diabetes rather than considering diabetic retinopathy solely as a medical problem, and to explore what we know and don't know about the ways diabetes affect the eye.  With the plethora of new information being generated, there are still a series of fundamental questions that must be addressed if effective treatments for diabetic retinopathy are to be found and applied.  Developed by a renowned group of authorities, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers responses and context for a range of questions, such as: do metabolic factors beyond glucose contribute to vision-threatening diabetic retinopathy? If so, how do these lead to vision impairment?  Is diabetic retinopathy a response to systemic metabolic abnormalities or are there unique ocular problems related to insulin resistance? What is the relationship between the neural, vascular, and inflammatory abnormalities in diabetic retinopathy? Do they represent a pathological cascade induced sequentially or simultaneous responses to one or more metabolic perturbations?  The authors note that if we do not address these types of questions, it is possible that the long process of developing new therapeutic

s will target only one arm of the pathology and leave the retina open to damaging consequences of the others. State-of-the-art, comprehensive, and an invaluable addition the research and clinical literature, Visual Dysfunction in Diabetes: The Science of Patient Impairment and Improvement offers guidance and a significant step toward new scientific approaches that can lessen the devastating vision impairment associated with diabetes.


Diabetes ERGs Microvascular Retinal Neovasularization Retinopathy Vascular Permeability

Editors and affiliations

  • Joyce Tombran-Tink
    • 1
  • Colin J. Barnstable
    • 2
  • Thomas W. Gardner
    • 3
  1. 1.Milton S. Hershey Medical Center, Dept. Neural and Behavioral SciencesPenn State College of MedicineHersheyUSA
  2. 2.Milton S. Hershey Medical Center, Dept. Neural and Behavioral SciencesPenn State College of MedicineHersheyUSA
  3. 3.Molecular and Integrative Physiology, Ophthalmology and Visual SciencesKellogg Eye CenterAnn ArborUSA

Bibliographic information

  • Book Title Visual Dysfunction in Diabetes
  • Book Subtitle The Science of Patient Impairment and Health Care
  • Editors Joyce Tombran-Tink
    Colin J. Barnstable
    Thomas W. Gardner
  • Series Title Ophthalmology Research
  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-60761-149-3
  • Softcover ISBN 978-1-4939-6168-9
  • eBook ISBN 978-1-60761-150-9
  • Edition Number 1
  • Number of Pages XV, 379
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Ophthalmology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


“It succeeds in summarizing recent advancements in our knowledge in the field with a well illustrated presentation, up-to-date references, and an authorship selected from an international group of respected investigators with proven contributions to the field. … It could be recommended as a reference for anyone interested in the basic mechanisms of the disease, its ocular manifestations, and treatment options.” (Radouil Tzekov, Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 253 (6), June, 2015)