© 2012

Sjögren’s Syndrome

Practical Guidelines to Diagnosis and Therapy

  • Robert I. Fox
  • Carla M. Fox
  • Integrates the experiences of international experts in the spectrum of involved disciplines

  • Offers a practical approach to the diagnosis and treatment of Sjögren’s Syndrome

  • Provides the latest information made possible only by multi-disciplinary communication

  • Presents a global perspective on this prevalent autoimmune disease


Table of contents

  1. Front Matter
    Pages i-xv
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Robert I. Fox, Carla M. Fox
      Pages 3-9
    3. Elke Theander, Frank A. Wollheim
      Pages 11-13
    4. Robert I. Fox, Manuel Ramos-Casals, John H. Stone
      Pages 15-34
    5. Robert I. Fox, Carla M. Fox
      Pages 35-56
  3. Classification Criteria and Disease Status Activity, Histology of Salivary Gland Biopsy, and Imaging

    1. Front Matter
      Pages 57-57
    2. Claudio Vitali, Chiara Baldini, Stefano Bombardieri
      Pages 59-72
    3. Roland Jonsson, Kathrine Skarstein, Malin V. Jonsson
      Pages 73-82
  4. Mechanisms of Pathogenesis

    1. Front Matter
      Pages 91-91
    2. Kathy L. Moser, John B. Harley
      Pages 93-110
    3. Kazuhisa Nozawa, Minoru Satoh, Seunghee Cha, Yoshinari Takasaki, Edward K. L. Chan
      Pages 111-132
    4. Athanasios G. Tzioufas, John G. Routsias, Haralampos M. Moutsopoulos
      Pages 133-149
    5. Yrjö T. Konttinen, Alberto Vivó Porcar, Pauliina Porola, Katja Koskenpato, María Lorés Rodriguez, Raimo Pöllänen et al.
      Pages 151-175
  5. Clinical and Therapeutic Considerations

    1. Front Matter
      Pages 177-177
    2. Paul E. Michelson, Robert I. Fox
      Pages 179-201
    3. Malin V. Jonsson, Nicolas Delaleu, Mihaela C. Marthinussen, Roland Jonsson
      Pages 221-242
    4. Nicolas Delaleu, Menelaos N. Manoussakis, Haralampos M. Moutsopoulos, Roland Jonsson
      Pages 243-267

About this book


The key knowledge assembled in this book comprises today’s most comprehensive resource on Sjögren’s syndrome.  Sjögren’s patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life.  This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others.


This practical clinical resource begins with an overview of Sjögren’s myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria.  The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics.  The third section is devoted to clinical manifestations and therapeutic considerations.  It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book’s contributors.  With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets.


Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjögren’s patients and physicians.


Autoimmune Rheumatology Sicca Sjogren's Syndrome Sjögren’s Syndrome

Editors and affiliations

  • Robert I. Fox
    • 1
  • Carla M. Fox
    • 2
  1. 1.Research Foundation, Rheumatology ClinicScripps Memorial Hospital &La JollaUSA
  2. 2.Research Foundation, Rheumatology ClinicScripps Memorial Hospital &La JollaUSA

Bibliographic information

  • Book Title Sjögren’s Syndrome
  • Book Subtitle Practical Guidelines to Diagnosis and Therapy
  • Editors Robert I. Fox
    Carla M. Fox
  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Springer, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-60327-956-7
  • Softcover ISBN 978-1-4939-3963-3
  • eBook ISBN 978-1-60327-957-4
  • Edition Number 1
  • Number of Pages XV, 506
  • Number of Illustrations 35 b/w illustrations, 41 illustrations in colour
  • Topics Rheumatology
    Internal Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews:

“This purpose is to present the most up-to-date information about Sjogren’s syndrome, its workup, extraglandular manifestations, and the latest diagnostic and therapeutic approaches. … The audience includes medical students, residents, fellows, and practitioners, particularly rheumatologists and internal medicine practitioners. … This book is very thorough in describing Sjogren’s syndrome and its extensive manifestations. As a rheumatology fellow, I found the book very useful in learning all there is to know about Sjogren’s syndrome.” (Maria Gonzalez-Mayda, Doody’s Review Service, February, 2012)