Horizontal Gene Transfer

Genomes in Flux

  • Maria Boekels Gogarten
  • Johann Peter Gogarten
  • Lorraine C. Olendzenski

Part of the Methods in Molecular Biology book series (MIMB, volume 532)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Lorraine Olendzenski, Johann Peter Gogarten
      Pages 3-9
  3. Definitions, Philosophy, and Implications of HGT

    1. Front Matter
      Pages 11-11
    2. Janet L. Siefert
      Pages 13-27
    3. Martin Iain Bahl, Lars Hestbjerg Hansen, Søren J. Sørensen
      Pages 73-102
    4. Maurizio Labbate, Rebecca Josephine Case, Hatch W. Stokes
      Pages 103-125
    5. Jinling Huang, Johann Peter Gogarten
      Pages 127-139
    6. Christopher H. House
      Pages 141-161
  4. Methods

    1. Front Matter
      Pages 193-193
    2. Diego Cortez, Luis Delaye, Antonio Lazcano, Arturo Becerra
      Pages 215-225
    3. Martin Iain Bahl, Gunnar Oregaard, Søren J. Sørensen, Lars Hestbjerg Hansen
      Pages 257-268
    4. Maia Larios-Sanz, Michael Travisano
      Pages 269-287
  5. Case Studies

    1. Front Matter
      Pages 307-307
    2. Shailaja Yerrapragada, Janet L. Siefert, George E. Fox
      Pages 339-366
    3. Margaret A. Riley, Michelle Lizotte-Waniewski
      Pages 367-377
    4. R. Thane Papke
      Pages 379-395
    5. Patricia A. Sobecky, Tracy H. Hazen
      Pages 435-453
    6. Patricia A. Sobecky, Jonna M. Coombs
      Pages 455-472
    7. U. Cecilia Alsmark, Thomas Sicheritz-Ponten, Peter G. Foster, Robert P. Hirt, T. Martin Embley
      Pages 489-500
    8. Makedonka Mitreva, Geert Smant, Johannes Helder
      Pages 517-535
  6. Back Matter
    Pages 537-551

About this book


Horizontal gene transfer (HGT) events encompass processes as varied as the exchange of genetic material between microbes coexisting in the same environment, between symbiotic bacteria and their eukaryotic hosts, and the evolution of organelles by symbiosis, in which whole genomes are acquired.  In Horizontal Gene Transfer: Genomes in Flux, expert researchers contribute an overview of HGT concepts as well as specific case histories that highlight the most current progress to inspire future work. Divided into three sections, the volume begins with an overview of terminology, concepts and the implications of HGT on current evolutionary thought and philosophy, and continues with methods involving computer and bioinformatics analyses of genomic data as well as molecular biology techniques for identifying, quantifying, and differentiating instances of HGT. A section of case studies follows, which provides detailed accounts of how HGT has shaped evolution across the diversity of organisms and organismal lineages. As a volume of the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.

Cutting-edge and thoroughly detailed, Horizontal Gene Transfer: Genomes in Flux examines how HGT has contributed to genome evolution and how understanding HGT impacts our ability to accurately reconstruct and comprehend the web-like evolutionary history in order to aid scientists in furthering their own research.


Adaptation Eukaryota bioinformatics cyanobacteria evolution gene expression gene transfer genes microbe microbes microbiology molecular biology

Editors and affiliations

  • Maria Boekels Gogarten
    • 1
  • Johann Peter Gogarten
    • 2
  • Lorraine C. Olendzenski
    • 3
  1. 1.University of ConnecticutMansfield CenterUSA
  2. 2.Dept. Molecular & Cell BiologyUniversity of ConnecticutStorrsUSA
  3. 3.Biology DepartmentSt. Lawrence UniversityCantonUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-852-2
  • Online ISBN 978-1-60327-853-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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