© 2010

Handbook of Drug-Nutrient Interactions

  • Joseph I. Boullata
  • Vincent T. Armenti

Part of the Nutrition and Health book series (NH)

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Approaching Drug-Nutrient Interactions

    1. Front Matter
      Pages 1-1
    2. Joseph I. Boullata
      Pages 3-26
    3. Robert B. Raffa
      Pages 27-43
    4. Richard H. Ho, Richard B. Kim
      Pages 45-84
    5. Thomas K.H. Chang
      Pages 85-117
    6. Stacey Milan, Francis E. Rosato Jr
      Pages 119-133
  3. Influence of Nutrition Status on Drug Disposition and Effect

    1. Front Matter
      Pages 135-135
    2. Charlene W. Compher, Joseph I. Boullata
      Pages 137-165
    3. Joseph I. Boullata
      Pages 167-205
  4. Influence of Food, Nutrients, or Supplementation on Drug Disposition and Effect

    1. Front Matter
      Pages 207-207
    2. David Fleisher, Burgunda V. Sweet, Ameeta Parekh, Joseph I. Boullata
      Pages 209-241
    3. Imad F. Btaiche, Burgunda V. Sweet, Michael D. Kraft
      Pages 303-339
  5. Influence of Medication on Nutrition Status, Nutrient Disposition, and Effect

    1. Front Matter
      Pages 425-425
    2. Jane M. Gervasio
      Pages 427-445

About this book


Handbook of Drug-Nutrient Interactions, Second Edition is an essential new work that provides a scientific look behind many drug-nutrient interactions, examines their relevance, offers recommendations, and suggests research questions to be explored. In the five years since publication of the first edition of the Handbook of Drug-Nutrient Interactions new perspectives have emerged and new data have been generated on the subject matter. Providing both the scientific basis and clinical relevance with appropriate recommendations for many interactions, the topic of drug-nutrient interactions is significant for clinicians and researchers alike. For clinicians in particular, the book offers a guide for understanding, identifying or predicting, and ultimately preventing or managing drug-nutrient interactions to optimize patient care.  Divided into six sections, all chapters have been revised or are new to this edition. Chapters balance the most technical information with practical discussions and include outlines that reflect the content; discussion questions that can guide the reader to the critical areas covered in each chapter, complete definitions of terms with the abbreviation fully defined and consistent use of terms between chapters. The editors have performed an outstanding service to clinical pharmacology and pharmaco-nutrition by bringing together a multi-disciplinary group of authors. Handbook of Drug-Nutrient Interactions, Second Edition is a comprehensive up-to-date text for the total management of patients on drug and/or nutrition therapy but also an insight into the recent developments in drug-nutrition interactions which will act as a reliable reference for clinicians and students for many years to come.


Drug absorption Drug disposition Drug metabolism Drug-nutrient interactions Pharmacodynamic Pharmacokinetic

Editors and affiliations

  • Joseph I. Boullata
    • 1
  • Vincent T. Armenti
    • 2
  1. 1.School of NursingUniversity of PennsylvaniaPhiladelphiaU.S.A.
  2. 2.Dept. SurgeryTemple University HospitalPhiladelphiaU.S.A.

Bibliographic information

  • Book Title Handbook of Drug-Nutrient Interactions
  • Editors Joseph I. Boullata
    Vincent T. Armenti
  • Series Title Nutrition and Health
  • Series Abbreviated Title Nutrition,Health
  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-60327-363-3
  • eBook ISBN 978-1-60327-362-6
  • Edition Number 2
  • Number of Pages XXVIII, 824
  • Number of Illustrations 11 b/w illustrations, 0 illustrations in colour
  • Topics Nutrition
  • Buy this book on publisher's site
Industry Sectors
Chemical Manufacturing


From the reviews of the second edition:

“The reference for physicians, pharmacists, nurses, dietitians, and related professionals in practice, research, or training, has been updated, some chapters even rewritten, to incorporate data and perspectives that have emerged during the five years since the first edition was prepared.” (SciTech Book News, March, 2010)

“This is a clinical pharmacology handbook covering drug-nutrient interactions. … Intended for clinicians, academicians, researchers, and students in medicine, pharmacy, nursing, and other health professions. … This handbook is extremely well referenced and provides a great documented history of the research in the drug-nutrient field. … Overall, this is an excellent book that is very well written. It fulfills its purpose of explaining and providing examples of drug-nutrient interactions. It is extensive and will be very useful to the reader.” (Philippe Colucci and Murray P. Ducharme, The Annals of Pharmacotherapy, Vol. 44, May, 2010)

“This book reviews all aspects of drug-nutrient interactions. … The book is written for all healthcare professionals, but this detail may be most appropriate for students and individuals who prescribe medications. … This comprehensive study of drug-nutrient interactions would be a good resource for those who require this level of depth.” (Amy Hess-Fischl, Doody’s Review Service, March, 2010)

“The Handbook of Drug Nutrient Interactions, Second Edition, addresses the complex interactions between both dietary components and their impact on drug absorption, distribution, and elimination as well as the effects of specific pharmacologic agents on nutritional health. … have produced a text that balances extremely technical information with practical advice. … provides health care professionals in all areas of practice, research, and education with a powerful resource. All nutritionally conscious health care professionals should have ready access to this compendium.” (Michael J. Glade, Nutrition, Vol. 26, 2010)

“This thorough, detailed volume covers virtually every aspect of nutrition and pharmacology. An excellent introduction reminds readers about the essentials of pharmacology and drug disposition. … The material on supplements is especially timely as more people turn to herbal and homeopathic self-medications to take control of their own health. Overall, this book is complete, well researched, and masterfully written. … This second edition will be an indispensable addition for many health science and physicians’ personal libraries. Summing Up: Essential. Graduate students and above.” (J. G. Schnellmann, Choice, Vol. 48 (2), October, 2010)

“The handbook will be useful for clinicians/physicians, pharmaceutical scientists and diet specialists … a general guide for understanding, identifying and managing drug-nutrient interactions. … reference text for those in related fields such as pharmacists, herbalists and physicians … . Important features of a handbook of this type are that the chapters are not too long, are up to date, easy to read, comprehensive and well referenced and these qualities will be found here. … This excellent handbook and reference book … can be thoroughly recommended.” (R. W. Lissner and A. M. Waaga-Gasser, International Journal of Clinical Pharmacology and Therapeutics, December, 2010)

“The present handbook is surely to be considered a benchmark that allows the readers to gain a fast, authoritative overview over this complex system of interactions among nutritional status, physiological and patho-physiological parameters, such as lifestyle, disease status, gender, route of administration, and food. … Handbook of Drug–Nutrient Interactions is truly helpful for clinicians, clinical pharmacologists and other healthcare providers as well as for scientists to orient themselves in this ‘jungle of potential interactions’ and should not be missing in any professional library.”­­­ (Jörn Schneede, European Journal of Clinical Pharmacology, Vol. 66, March, 2010)