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The Dopamine Receptors

  • Kim A. Neve

Part of the The Receptors book series (REC)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Irina S. Moreira, Lei Shi, Zachary Freyberg, Spencer S. Ericksen, Harel Weinstein, Jonathan A. Javitch
    Pages 47-73
  3. Olaf Prante, Miriam Dörfler, Peter Gmeiner
    Pages 101-135
  4. Robert J. Romanelli, John T. Williams, Kim A. Neve
    Pages 137-173
  5. Melissa L. Perreault, Vaneeta Verma, Brian F. O’Dowd, Susan R. George
    Pages 193-217
  6. Lisa A. Hazelwood, R. Benjamin Free, David R. Sibley
    Pages 219-254
  7. Kjell Fuxe, Daniel Marcellino, Diego Guidolin, Amina Woods, Luigi Agnati
    Pages 255-280
  8. Carlos Cepeda, Véronique M. André, Emily L. Jocoy, Michael S. Levine
    Pages 281-302
  9. Emanuele Tirotta, Claudia De Mei, Chisato Iitaka, Maria Ramos, Dawn Holmes, Emiliana Borrelli
    Pages 303-322
  10. Gerard J. O’Sullivan, Colm O’Tuathaigh, Katsunori Tomiyama, Noriaki Koshikawa, John L. Waddington
    Pages 323-371
  11. Jeremy K. Seamans, Trevor W. Robbins
    Pages 373-398
  12. Anissa Abi-Dargham, Marc Laruelle
    Pages 399-430
  13. Nathalie Ginovart, Shitij Kapur
    Pages 431-477
  14. Eugenia V. Gurevich, Vsevolod V. Gurevich
    Pages 525-584
  15. Frankie H.F. Lee, Albert H.C. Wong
    Pages 585-632
  16. Back Matter
    Pages 633-647

About this book

Introduction

Dopamine receptors are among the most validated drug targets for neuropsychiatric disorders such as schizophrenia and Parkinson’s disease, and are potential targets for other disorders such as substance abuse, depression, Tourette’s syndrome, and attention deficit hyperactivity disorder. The new knowledge brought from the creation and characterization of mice deficient in each of the subtypes and the development of increasingly subtype-selective agonists and antagonists has fueled many of the chapters new to this second edition, with the use of knock-out mice and subtype-selective drugs meriting discussion in stand-alone chapters. The field of G protein-coupled receptors has also advanced significantly since the first edition, with a model of GPCR signaling based on linear, compartmentalized pathways having been replaced by a more complex, richer model in which neurotransmitter effects are mediated by a signalplex composed of numerous signaling proteins, including multiple GPCRs, other types of receptors, such as ionotropic receptors, accessory and scaffolding proteins, and effectors. This second edition of Dopamine Receptors will be of interest to neurobiologists, pharmacologists and molecular biologists who study the brain, as well as neurologists working on psychiatric diseases.

Keywords

Parkinson Psychopharmacology attention deficit hyperactivity disorder (ADHD) dopamine neurons physiology receptors

Editors and affiliations

  • Kim A. Neve
    • 1
  1. 1.Portland VA Medical Center (R & D-30)PortlandU.S.A.

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60327-333-6
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-60327-332-9
  • Online ISBN 978-1-60327-333-6
  • Series Print ISSN 1048-6909
  • Series Online ISSN 2524-6488
  • Buy this book on publisher's site
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