© 2008

The Metabolic Syndrome

Epidemiology Clinical Treatment and Underlying Mechanisms

  • Barbara Caleen Hansen
  • George A. Bray

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Metabolic Syndrome—Past and Future

    1. Barbara Caleen Hansen, Rosemary Peternel, George A. Bray
      Pages 1-7
  3. Epidemilogy And Clinical Treatment: Issues In Defining And Treating The Metabolic Syndrome

  4. Endothelial Function, Inflammation, and Dyslipidemia

    1. Front Matter
      Pages 105-105
    2. Kieren J. Mather, Alain Baron, Michael J. Quon
      Pages 107-135
    3. Yiqing Song, Simin Liu, Joann E. Manson
      Pages 167-188
    4. Christian X. Andersson, Ann Hammarstedt, Per-Anders Jansson, Ulf Smith
      Pages 189-204
    5. Tina J. Chahil, Gissette Reyes, Henry N. Ginsberg
      Pages 205-218
  5. Insulin—Secretion and Action: Underlying Mechanisms of the Metabolic Syndrome

    1. Front Matter
      Pages 219-219
    2. Anne Clark, Jenni Moffitt, Lianne Van De Laar, Katherine Pinnick, Farhina Sayyed
      Pages 221-232
    3. Jens Juul Holst, Filip Krag Knop
      Pages 233-254
    4. E. W. Kraegen, G. J. Cooney, Jiming M. Ye, Stuart M. Furler
      Pages 307-328

About this book


With an extraordinary need for early intervention and prevention to slow or halt its progression, Metabolic Syndrome is one of the most challenging health problems. Only through an understanding of the science underlying this syndrome can successful interventions be developed and implemented. In The Metabolic Syndrome: Epidemiology, Clinical Treatment, and Underlying Mechanisms, the writers stimulate new thinking concerning underlying mechanisms and encourage heightened efforts to develop new therapeutics, potentially targeting uniquely intersecting pathways. Developing this new synthesis and analysis of the Metabolic Syndrome will bring together the viewpoints of epidemiologists, physiologists, molecular biologists/biochemists, and clinicians toward understanding the current state of knowledge of both the causes and consequences of the Metabolic Syndrome.


Cardiology Diabetes Endocrinology Metabolism cardiovascular endothelium insulin pathophysiology physiology surgery

Editors and affiliations

  • Barbara Caleen Hansen
    • 1
  • George A. Bray
    • 2
  1. 1.Obesity, Diabetes, and Aging Research CenterUniversity of South Florida College of MedicineTampa
  2. 2.Pennington Biomedical Research CenterLouisiana State UniversityBaton Rouge

Bibliographic information

  • Book Title The Metabolic Syndrome
  • Book Subtitle Epidemiology Clinical Treatment and Underlying Mechanisms
  • Editors Barbara C. Hansen
    George A. Bray
  • Series Title Contemporary Endocrinology
  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-738-9
  • Softcover ISBN 978-1-61737-750-1
  • eBook ISBN 978-1-60327-116-5
  • Edition Number 1
  • Number of Pages XII, 402
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Endocrinology
    Internal Medicine
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews:

"This book presents a balanced view of the controversies surrounding the metabolic syndrome and supplies the reader with a detailed account of the key issues that divide the various camps. … is an admirable collection of scientifically focused and up-to-date views of the current thinking on the metabolic syndrome. It can be recommended for scientists working in this field as well as for clinicians who wish to gain a deeper understanding of this complex syndrome." (Arne Astrup, The New England Journal of Medicine, July, 2008)

"This book covers three major perspective of the metabolic syndrome … . this book is written for an endocrinology audience and anyone who has a strong interest in the link between the basic science of insulin resistance and the clinical manifestations of the metabolic syndrome. Practitioners will find useful information about the underlying mechanisms of the disease as well as an overview of treatment approaches. … This is a high quality review of insulin resistance targeted at endocrinologists and basic scientists." (Matthew J. Sorrentino, Doody’s Review Service, November, 2008)