Essential Concepts in Toxicogenomics

  • Donna L. Mendrick
  • William B. Mattes

Part of the Methods in Molecular Biology™ book series (MIMB, volume 460)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Michael Elashoff
    Pages 69-87
  3. Scott A. Barros, Rory B. Martin
    Pages 89-112
  4. Mark W. Porter
    Pages 113-143
  5. Lyle D. Burgoon, Timothy R. Zacharewski
    Pages 145-157
  6. John N. Calley, William B. Mattes, Timothy P. Ryan
    Pages 159-183
  7. Marc F. DeCristofaro, Kellye K. Daniels
    Pages 185-194
  8. Donna L. Mendrick
    Pages 195-220
  9. William B. Mattes
    Pages 221-238
  10. Back Matter
    Pages 263-277

About this book


The field of toxicogenomics has been growing quickly, yet with rapid growth comes the need to periodically reflect on the nature of the field.  Essential Concepts in Toxicogenomics collects reviews, opinion pieces and case studies from the leading experts in this dynamic field with a focus on its application to pharmaceuticals.  Topics covered include issues that affect the quality of toxicogenomics experiments, statistical approaches to their data analysis, the use of such data to build toxicogenomic models, and the utilization of genomics to identify biomarkers within the preclinical and clinical arenas. Although not in the standard Methods in Molecular Biology™ series format, this volume retains the practicality and usefulness of the highly successful series.


Informative and cutting-edge, Essential Concepts in Toxicogenomics is an ideal resource for pharmaceutical companies, chemical manufacturers, toxicologists, and all who must keep up-to-date on progress in this vital and important field.


Annotation Biomarkers Genomic data Microarray Regulatory implications Toxicity Toxicogenomic models Translation bioinformatics genes genome molecular biology

Editors and affiliations

  • Donna L. Mendrick
    • 1
  • William B. Mattes
    • 2
  1. 1.Gene Logic IncGaithersburgUSA
  2. 2.The Critical Path InstituteRockvilleUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-638-2
  • Online ISBN 978-1-60327-048-9
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals