© 2008

Biopharmaceutical Drug Design and Development

  • Susanna Wu-Pong
  • Yon Rojanasakul


  • Comprehensive examination of the newest biopharmaceutical drugs

  • Detailed investigation of revolutionary inventions and techniques, including cloning and microarray technology

  • Review of the Human Genome Project


Table of contents

  1. Front Matter
    Pages i-x
  2. Susanna Wu-Pong
    Pages 1-14
  3. Susanna Wu-Pong
    Pages 15-29
  4. Susanna Wu-Pong, Rita Shiang
    Pages 31-45
  5. Neelam Azad, Anand Krishnan V. Iyer, Yon Rojanasakul
    Pages 47-66
  6. Wagner Dos Santos, Helen L. Fillmore
    Pages 121-139
  7. Jingjiao Guan, Xiaogang Pan, L. James Lee, Robert J. Lee
    Pages 141-173
  8. Helen L. Fillmore, Susanna Wu-Pong
    Pages 175-191
  9. A. Yin Zhang, Susanna Wu-Pong
    Pages 193-221
  10. Robert C. Tam, Zhi Hong, Miriana Moran, Andrei Varnavski, Sung-Kwon Kim
    Pages 223-251
  11. Kai I. Cheang
    Pages 253-266
  12. Neelam Azad, Yon Rojanasakul
    Pages 293-323
  13. Richard E. Lowenthal, Robert G. Bell
    Pages 325-343
  14. Back Matter
    Pages 367-375

About this book


Biopharmaceutical Drug Design and Development, Second Edition, updates the widely successful first edition, published in 1999. This new, expanded edition investigates the dozens of new biopharmaceutical drugs that have become available since the publication of the first edition. Among the drugs discussed are ones in the categories of monoclonal antibodies for in-vivo use, cytokines, growth factors, enzymes, immunomodulators, thrombolytics, and immonotherapies including vaccines. Additionally, the volume examines new and emerging technologies, such as bioinformatics, DNA microarrays, transgenics, therapeutic gene delivery, stem cells, nucleic acid-based therapeutics, and macromolecular drug delivery. Authors also study pharmacogenetics in the clinic and changes in biologic drug approval at the FDA. Biopharmaceutical Drug Design and Development, Second Edition, is a worthy sequel in the discussion on the dynamic, exciting field of biotechnology.


DNA Microarray Monoclonal Antibodies bioinformatics enzymes genes tissue

Editors and affiliations

  • Susanna Wu-Pong
    • 1
    • 2
  • Yon Rojanasakul
    • 3
  1. 1.Pharmaceutical Sciences Graduate Programs Department of Pharmaceutics, School of PharmacyVirginia Commonwealth UniversityRichmond
  2. 2.Virginia Commonwealth UniversityRichmond
  3. 3.Department of Basic Pharmaceutical SciencesWest Virginia UniversityMorgantown

Bibliographic information

Industry Sectors
Health & Hospitals
Pharmacology & Toxicology
Consumer Packaged Goods


From the reviews of the second edition:

"The book comprises 16 chapters written by 24 authors from academic and industrial laboratories in the U.S. The book is suitable for a wide audience of industrial and academic pharmaceutical scientists interested in a broad introduction to biopharmaceutical technology within the context of drug design and development. … Overall, the book is well written with an excellent nine-page index. The chapters are generally well illustrated. … it would be a valuable addition to industrial and academic libraries." (Aliasger K. Salem, Journal of Medicinal Chemistry, Vol. 51 (19), 2008)

"This book is an update of the first edition of Biopharmaceutical Drug Development … . this book is dedicated to quite detailed discussion of the impact the various ‘omic’ technologies have had on drug discovery and design. … Overall, this is quite a useful reference book for toxicologists working in the biopharmaceutical sector, particularly if they are still getting to grips with the various ‘omics’ technologies and areas such stem cell therapy and gene silencing." (Peter Ryle, British Toxicological Society Newsletter, June-August, 2009)