© 2007

Introduction to Systems Biology

  • Sangdun Choi


  • Basic explanation of how to use computational methods to explain underlying biological meanings

  • Introduction into state-of-the-art systems biology

  • Contains typical approaches to experimental design, both wet-lab and computational


Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Hiroaki Kitano
      Pages 3-13
    3. Ines Thiele, Bernhard Ø. Palsson
      Pages 14-36
    4. Ana Paula Oliveira, Michael C. Jewett, Jens Nielsen
      Pages 37-66
  3. Experimental Techniques for Systems Biology

    1. Front Matter
      Pages 67-67
    2. Nils Blüthgen, Szymon M. Kielbasa, Dieter Beule
      Pages 69-84
    3. Yuki Hasegawa, Yoshihide Hayashizaki
      Pages 85-105
    4. Vijayalakshmi H. Nagaraj, Anirvan M. Sengupta
      Pages 106-123
    5. Hong-wu Ma, Marcio Rosa da Silva, Ji-Bin Sun, Bharani Kumar, An-Ping Zeng
      Pages 124-146
    6. Gaëlle Lelandais, Stéphane Le Crom
      Pages 147-159
    7. Keiji Kito, Takashi Ito
      Pages 160-182
    8. Ting Zhao, Shann-Ching Chen, Robert F. Murphy
      Pages 196-214
  4. Theoretical and Modeling Techniques

    1. Front Matter
      Pages 215-215
    2. Matthew J. Beal, Juan Li, Zoubin Ghahramani, David L. Wild
      Pages 217-241
    3. Noriko Hiroi, Akira Funahashi
      Pages 261-281
    4. Nils Blüthgen, Stefan Legewie, Hanspeter Herzel, Boris Kholodenko
      Pages 282-299

About this book


Introduction to Systems Biology is an introductory text for undergraduate and graduate students who are interested in comprehensive biological systems. The authors provide a broad overview of the field using key examples and typical approaches to experimental design. The volume begins with an introduction to systems biology and then details experimental omics tools. Other sections introduce the reader to challenging computational approaches to help understand biological dynamic systems. The final sections of the volume provide ideas for theoretical and modeling optimization in systemic biological researches, presenting most algorithms as implementations, including an up-to-date full range of bioinformatic programs and available successful applications.

Informative and cutting-edge, this volume presents a clear and intuitive illustration of the biological systemic approaches and introduces ideal computational methods for research. Introduction to Systems Biology is an indispensable resource, providing a first glimpse into the state-of-the-art in systems biology.


Evolution Proteomics Termination biology gene expression genes signal transduction transcription

Editors and affiliations

  • Sangdun Choi
    • 1
  1. 1.Department of Biological SciencesAjou UniversitySuwonKorea

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