Comparative Genomics

  • Nicholas H. Bergman

Part of the Methods In Molecular Biology™ book series (MIMB, volume 396)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Comparative Analysis of Domain and Protein Families

    1. Front Matter
      Pages 1-1
    2. Philipp Pagel, Normann Strack, Matthias Oesterheld, Volker Stümpflen, Dmitrij Frishman
      Pages 3-15
    3. Sophie Pasek
      Pages 17-29
    4. Jaina Mistry, Robert Finn
      Pages 43-58
    5. Nicola Mulder, Rolf Apweiler
      Pages 59-70
    6. Kiyoko F Aoki-Kinoshita, Minoru Kanehisa
      Pages 71-91
  3. Orthologs, Synteny, and Genome Evolution

    1. Front Matter
      Pages 93-93
    2. Giulio Pavesi, Graziano Pesole
      Pages 111-119
    3. Lung Lu Chin, Chih Lin Ying, Lin Huang Yen, Yi Tang Chuan
      Pages 121-134
    4. Aaron E Darling, Todd J Treangen, Xavier Messeguer, Nicole T Perna
      Pages 135-152
    5. Volker Brendel, Stefan Kurtz, Xioakang Pan
      Pages 153-163
    6. Thomas Schmidt, Jens Stoye
      Pages 165-182
  4. Experimental Analysis of Whole Genomes: Analysis of Copy Number and Sequence Polymorphisms

    1. Front Matter
      Pages 183-183
    2. Paul van den IJssel, Bauke Ylstra
      Pages 207-221
    3. Eduardo N. Taboada, Christian C. Luebbert, John H.E. Nash
      Pages 223-253
    4. Brian W. Brunelle, Tracy L. Nicholson
      Pages 267-279
    5. Honghua Li, Hui-Yun Wang, Xiangfeng Cui, Minjie Luo, Guohong Hu, Danielle M. Greenawalt et al.
      Pages 281-294
    6. Xiaofeng Zhou, David T.W. Wong
      Pages 295-314
    7. Farnaz Absalan, Mostafa Ronaghi
      Pages 315-330
    8. Peter De Rijk, Jurgen Del-Favero
      Pages 331-344
    9. Tianhua Niu
      Pages 359-369
    10. Medha Bhagwat
      Pages 371-393
    11. Siamak P. Yazdankhah, Bjørn-Arne Lindstedt
      Pages 395-405
    12. Knud Nairz, Peder Zipperlen, Manuel Schneider
      Pages 419-432
  5. Back Matter
    Pages 433-434

About this book


Comparative Genomics, Volume 2, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes. Given the tremendous increase in available biosequence data over the past ten years, Comparative Genomics, Volume 1, is timely, comprehensive, and novel. A companion Volume 1 is also available from Humana Press.


DNA Evolution Genotyp Microarray Nucleotide SNP Single Nucleotide Polymorphism genes hybridization proteins

Editors and affiliations

  • Nicholas H. Bergman
    • 1
  1. 1.Bioinformatics Program and Department of Microbiology and ImmunologyUniversity of Michigan Medical SchoolAnn Arbor

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-934115-37-4
  • Online ISBN 978-1-59745-515-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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