© 2007

Patch-Clamp Analysis

Advanced Techniques

  • Wolfgang Walz


  • Provides readily reproducible, step-by-step protocols that ensure experimental success

  • Describes methods combining patch-clamp with molecular biology and imaging

  • Includes new state-of-the-art techniques


Part of the Neuromethods book series (NM, volume 38)

Table of contents

  1. Front Matter
    Pages i-x
  2. Richard A. Levis, James L. Rae
    Pages 1-34
  3. Harald Sontheimer, Michelle L. Olsen
    Pages 35-68
  4. David J.A. Wyllie
    Pages 69-119
  5. Hartmut Schmidt, Jens Eilers
    Pages 121-148
  6. Dmitry V. Sarkisov, Samuel S.-H. Wang
    Pages 149-168
  7. James R. Moyer Jr., Thomas H. Brown
    Pages 169-227
  8. Hidemasa Furue, Toshihiko Katafuchi, Megumu Yoshimura
    Pages 229-251
  9. Constantine Sarantopoulos
    Pages 253-293
  10. Manfred Heckmann, Stefan Hallermann
    Pages 295-307
  11. Srinivas M. Tipparaju, Aruni Bhatnagar
    Pages 309-324
  12. Héctor G. Marrero, José R. Lemos
    Pages 325-352
  13. Guiying Cui, Matthew D. Fuller, Christopher H. Thompson, Zhi-Ren Zhang, Nael A. McCarty
    Pages 353-371
  14. Jan C. Behrends, Niels Fertig
    Pages 411-433
  15. Michael Fejtl, Uwe Czubayko, Alexander Hümmer, Tobias Krauter, Albrecht Lepple-Wienhues
    Pages 435-450
  16. Back Matter
    Pages 451-475

About this book


Continuing the research of the best-selling first edition, Patch-Clamp Analysis: Advanced Techniques, Second Edition collects three more years of research in the ever-expanding study of the cell membrane. With the latest developments in the "traditional" patch techniques such as whole-cell and single channel as well as perforated patch, fast drug application, loose patch and macropatch techniques, this authoritative second edition updates the standard techniques while introducing three brand new, cutting-edge technical advances in the field.

Thorough and timely, Patch-Clamp Analysis: Advanced Techniques, Second Edition is an invaluable resource for neuroscientists attempting to discover and understand the long-hidden complexities of the cell.


PCR brain cell development drug membrane physiology research

Editors and affiliations

  • Wolfgang Walz
    • 1
  1. 1.Department of PhysiologyUniversity of SaskatchewanSaskatoonCanada

Bibliographic information

  • Book Title Patch-Clamp Analysis
  • Book Subtitle Advanced Techniques
  • Editors Wolfgang Walz
  • Series Title Neuromethods
  • DOI
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Hardcover ISBN 978-1-58829-705-1
  • Softcover ISBN 978-1-61737-728-0
  • eBook ISBN 978-1-59745-492-6
  • Series ISSN 0893-2336
  • Series E-ISSN 1940-6045
  • Edition Number 2
  • Number of Pages X, 475
  • Number of Illustrations 97 b/w illustrations, 0 illustrations in colour
  • Topics Neurosciences
    Human Physiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


From the reviews of the second edition:

"This book, edited by an outstanding expert in biophysics, and written by a large number of well-recognized contributors, is a complete text on this most important technique. … this excellent neuroscience book brings discussion of this most important technique up-to-date and discusses the current and future prospects in this field. … Patch clamp testing is becoming increasingly important in medical research. For this reason, this book can be highly recommended to medical-biological investigators." (Julian L. Ambrus and Clara M. Ambrus, The Journal of Medicine, February, 2008)