The Molecular Basis of Human Cancer

  • William B. Coleman
  • Gregory J. Tsongalis

Table of contents

  1. Front Matter
    Pages i-xix
  2. William B. Coleman, Gregory J. Tsongalis
    Pages 1-24
  3. Claudine L. Lefferts, Joel A. Lefferts
    Pages 25-42
  4. Jonathan R. Pollack
    Pages 43-63
  5. Thomas Ried, Kerstin Heselmeyer-Haddad, Jordi Camps, Timo Gaiser
    Pages 65-82
  6. Thomas Mikeska, Alexander Dobrovic
    Pages 83-102
  7. Jeffrey M. Lake, Timothy D. Veenstra
    Pages 103-119
  8. Ashley G. Rivenbark
    Pages 121-142
  9. Dean W. Felsher, Constadina Arvanitis, Pavan Bendapudi, Pavan Bachireddy
    Pages 143-157
  10. Manjari Dimri, Goberdhan P. Dimri
    Pages 183-196
  11. Monte S. Willis, Nancy Klauber-DeMore
    Pages 197-202
  12. Danny R. Welch, Douglas R. Hurst
    Pages 203-216
  13. Christophe Béroud
    Pages 217-230
  14. Richard A. Hubner, Richard S. Houlston
    Pages 231-239
  15. Kazuma Ohyashiki, Masahiko Kuroda, Junko H. Ohyashiki
    Pages 241-262
  16. José Ignacio Martín-Subero, Manel Esteller
    Pages 263-275
  17. Phong Trang, Joanne B. Weidhaas, Frank J. Slack
    Pages 277-286
  18. Paul F. Lambert
    Pages 297-306
  19. William A. Ricke, Karin Williams, Jalissa Wynder, Ganesh Palapattu, Yuzhuo Wang, Gerald R. Cunha
    Pages 307-322
  20. Clemens B. Tempfer, Marc-André Reymond
    Pages 323-334
  21. Zoran Gatalica, Anatole Ghazalpour, Stan L. Lilleberg, Jeffrey Swensen, Henry T. Lynch
    Pages 335-353
  22. J. William Harbour
    Pages 355-361
  23. Sonia S. Kupfer, Nathan A. Ellis
    Pages 381-400
  24. Michael P. Lux, Mayada R. Bani, Peter A. Fasching, Matthias W. Beckmann
    Pages 401-421
  25. Smitha Dutt, Allen C. Gao
    Pages 423-445
  26. Kwun M. Fong, Jill E. Larsen, Casey Wright, Krishna Sriram, Morgan Davidson, Marissa Daniels et al.
    Pages 447-496
  27. Alessia Pacifico, Giovanni Leone, Honnavara N. Ananthaswamy
    Pages 497-503
  28. L. Jeffrey Medeiros, Sergej N. Konoplev
    Pages 505-559
  29. John Hunt, Yuri Fedoriw, William N. Rezuke
    Pages 561-587
  30. Amy D. Brockmeyer, Louis Dubeau
    Pages 603-621
  31. José Luis Ordóñez, Daniel Osuna, Juan Madoz-Gúrpide, Enrique de Álava
    Pages 623-655
  32. Daniel Coluccia, Adrienne Weeks, Javier Fandino, Christian Schneider, Christian Smith, James T. Rutka
    Pages 657-694
  33. Zhuo (Georgia) Chen, Suresh Ramalingam, Dong M. Shin
    Pages 709-726
  34. Joshua E. Allen, Wafik S. El-Deiry
    Pages 727-756
  35. Francesco Torino, Roberta Sarmiento, Raffaelle Longo, Giampietro Gasparini
    Pages 757-769
  36. Xin Chen, Jian Jin
    Pages 771-795
  37. Christos Patriotis, Padma Maruvada, Sudhir Srivastava
    Pages 797-809
  38. Anand C. Annan, Paul B. Fisher, Paul Dent, Gene P. Siegal, David T. Curiel
    Pages 811-841
  39. Scott A. Turner, Gregory J. Tsongalis
    Pages 843-855
  40. Back Matter
    Pages 857-873

About this book


This book covers the concepts of molecular medicine and personalized medicine. Subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. These chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. The volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care.

The Molecular Basis of Human Cancer, Second Edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.


Sporadic Cancer Cancer Genomics Hormonal Carcinogenesis Hereditary Cancer Cancer Drug Discovery

Editors and affiliations

  • William B. Coleman
    • 1
  • Gregory J. Tsongalis
    • 2
  1. 1.Department of Pathology and Laboratory Medicine, Curriculum in Toxicology, UNC Program in Translational Medicine, UNC Lineberger Comprehensive CenterUniversity of North Carolina School of MedicineChapel HillUSA
  2. 2.Laboratory for Clinical Genomics and Advanced Technology (CGAT), Department of Pathology and Laboratory MedicineDartmouth-Hitchcock Medical Center, Norris Cotton Cancer Center, Geisel School of Medicine at DartmouthLebanon, HanoverUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-1-934115-18-3
  • Online ISBN 978-1-59745-458-2
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology