Deep Brain Stimulation in Neurological and Psychiatric Disorders

  • Daniel Tarsy
  • Jerrold L. Vitek
  • Philip A. Starr
  • Michael S. Okun

Part of the Current Clinical Neurology book series (CCNEU)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Overview of Deep Brain Stimulation

    1. Mustafa Saad Siddiqui, Thomas Ellis, Stephen S. Tatter, Kelly D. Foote, Michael S. Okun
      Pages 83-98
    2. Frank Steigerwald, Jens Volkmann
      Pages 111-134
    3. Svjetlana Miocinovic, Cameron C. McIntyre, Marc Savasta, Jerrold L. Vitek
      Pages 151-177
  3. Deep Brain Stimulation in Movement Disorders

    1. Kelly E. Lyons, Rajesh Pahwa
      Pages 205-214
    2. Erwin B. Montgomery Jr.
      Pages 215-227
    3. Daniel Tarsy, Efstathios Papavassiliou, Kelly E. Lyons, Rajesh Pahwa
      Pages 229-241
    4. Frances Weaver, Kenneth Follett, Matthew Stern
      Pages 243-252
    5. Ludy Shih, Daniel Tarsy
      Pages 291-303
    6. Marie Vidailhet, David Grabli, Emmanuel Roze
      Pages 305-319
    7. Linda Ackermans, Yasin Temel, Veerle Visser-Vandewalle
      Pages 321-332
  4. Postoperative Management in Patients Undergoing Deep Brain Stimulation

    1. Ioannis U. Isaias, Michele Tagliati
      Pages 361-397
    2. Alexander I. Tröster, April B. McTaggart, Ines A. Heber
      Pages 399-452
    3. Kenneth B. Baker, Michael D. Phillips
      Pages 453-472
    4. Jay L. Shils, Ron L. Alterman, Jeffrey E. Arle
      Pages 473-494
  5. Deep Brain Stimulation in Other Indications

    1. Loes Gabriëls, Kris van Kuyck, Marleen Welkenhuyzen, Paul Cosyns, Bart Nuttin
      Pages 531-546
    2. Philip A. Starr, Andrew Ahn
      Pages 547-560
    3. William J. Marks Jr.
      Pages 561-569
    4. Julie G. Pilitsis, Roy A. E. Bakay
      Pages 571-591
  6. Back Matter
    Pages 593-601

About this book


Written by renowned authorities in the field, Deep Brain Stimulation in Neurological and Psychiatric Disorders discusses today’s most current and cutting-edge applications of DBS. Initially used to treat Parkinson’s disease and essential tremor, DBS now has new clinical indications, new anatomic targets, and new technologies that enable an expanded role for DBS in the treatment of other movement disorders such as dystonia, and for other neurologic disorders such as epilepsy, Tourette syndrome and cluster headache. Early experience has also been reported for psychiatric syndromes, such as obsessive-compulsive disorder and depression. This important book begins with reviews of the functional anatomy and physiology of motor and nonmotor aspects of the basal ganglia and their connections which underlie the application of DBS to neurological and psychiatric disorders. This is followed by proposed mechanisms of action of DBS based on functional neuroimaging and neurophysiologic studies in animals and man. Discussions of patient selection, preoperative assessment, operative complications and brain targeting are followed by chapters concerning the demands of microelectrode mapping as well as new and emerging brain imaging approaches for target localization inside the operating room. Postoperative management and outcomes are reviewed in a series of chapters concerning immediate and delayed complications. Particularly important chapters on programming, DBS safety with regard to MRI and other electronic devices, neuropsychological sequelae, and quality of life are also included. Finally, new areas of DBS application are addressed by experts with experience in Tourette syndrome, epilepsy, obsessive-compulsive disorder, depression, and cluster headache. Comprehensive and state-of-the-art, Deep Brain Stimulation in Neurological and Psychiatric Disorders provides a balanced and level-headed approach to the use of DBS with emphasis on proper and objective assessment of outcomes, particularly in regard to the new and emerging applications -- all with the main goal of providing patients with some measure of relief from their difficult conditions.


Basal ganglia Cluster headache Deep brain stimulation Depression Epilepsy Microelectrode mapping Neurological Obsessive-compulsive disorder Parkinson Psychiatric Syndrom Tourette Syndrome

Editors and affiliations

  • Daniel Tarsy
    • 1
  • Jerrold L. Vitek
    • 2
  • Philip A. Starr
    • 3
  • Michael S. Okun
    • 4
  1. 1.Parkinson's Disease and Movement Disorders Center, Department of Neurology, Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonUSA
  2. 2.Neuromodulation Research Center, Lerner Research InstituteThe Cleveland Clinic FoundationClevelandUSA
  3. 3.Department of NeurosurgeryUniversity of CaliforniaSan FranciscoUSA
  4. 4.Departments of Neurology and Neurosurgery, McKnight Brain InstituteUniversity of FloridaGainesvilleUSA

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