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Stem Cells and Myocardial Regeneration

  • Book
  • © 2007

Overview

Editors:
  1. Marc S. Penn

    1. Bakken Heart Brain Institute and Coronary Intensive Care Unit, The Cleveland Clinic Foundation Cleveland

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Part of the book series: Contemporary Cardiology (CONCARD)

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Table of contents (21 chapters)

  1. Stem Cell-Based Clinical Trials For Cardiac Dysfunction

    1. Chronic Heart Failure

      1. Whole Bone Marrow Transplantation
        • Emerson C. Perin, Guilherme V. Silva
        Pages 223-244
      2. Clinical Angioblast Therapy
        • Amit N. Patel, Jorge Genovese
        Pages 245-258
      3. Use of Skeletal Myoblasts for the Treatment of Chronic Heart Failure
        • Anthony W. Ashton, David D’Alessandro, Robert E. Michler
        Pages 259-274

    2. Acute Myocardial Infarction

      1. Bone Marrow and Angioblast Transplantation
        • Marc S. Penn, Samuel Unzek, Niladri Mal, Kai Wang
        Pages 277-284
      2. Strategies for Cytokine Modification and Stem Cell Mobilization for Acute Myocardial Infarction
        • Stephen G. Ellis, Brian J. Bolwell
        Pages 285-294

  2. Summary/Future Challenges

    1. Front Matter

      Pages 295-295
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    2. Summary and Future Challenges

      • Marc S. Penn
      Pages 297-302

  3. Back Matter

    Pages 303-316
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Keywords

About this book

Over the past 5 years there has been great excitement and controversy in the scientific, financial, and lay literature for the potential of stem cell-based strategies for the prev- tion and treatment of chronic heart failure (CHF). Not that long ago we believed we were born with a set number of cardiac myocytes and that once damaged there was no hope to replace them. The interest in the field stems from the magnitude of cardiovascular disease in the world. Our ability to treat and help patients survive acute myocardial infarction (MI) has resulted in a near epidemic of CHF. There are more than 5 million Americans who currently carry the diagnosis of CHF. With more than 1 million MIs a year in the United States, there are approx 500,000 new cases of CHF diagnosed each year. The goal of Stem Cells and Myocardial Regeneration is to present, in a coherent manner, the current state of knowledge of stem cell-based therapies for cardiac dysfunction, including current findings in both the laboratory and the clinic trials. The first section of this Stem Cells and Myocardial Regeneration focuses on the magnitude of the problem and the successes and failures of what we consider optimal medical therapy. It is on this background that stem cell-based therapy needs to build.

Editors and Affiliations

  • Bakken Heart Brain Institute and Coronary Intensive Care Unit, The Cleveland Clinic Foundation Cleveland

    Marc S. Penn

Bibliographic Information

  • Book Title: Stem Cells and Myocardial Regeneration

  • Editors: Marc S. Penn

  • Series Title: Contemporary Cardiology

  • DOI: https://doi.org/10.1007/978-1-59745-272-4

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-1-58829-664-1Published: 01 October 2006

  • Softcover ISBN: 978-1-61737-705-1Published: 10 December 2010

  • eBook ISBN: 978-1-59745-272-4Published: 06 November 2007

  • Series ISSN: 2196-8969

  • Series E-ISSN: 2196-8977

  • Edition Number: 1

  • Number of Pages: 400

  • Number of Illustrations: 57 b/w illustrations, 10 illustrations in colour

  • Topics: Cardiology

  • Industry Sectors: Biotechnology, Engineering, Finance, Business & Banking, Health & Hospitals, Pharma

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