Prostate Cancer

Biology, Genetics, and the New Therapeutics

  • Leland W. K. Chung
  • William B. Isaacs
  • Jonathan W. Simons

Part of the Contemporary Cancer Research book series (CCR)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Biology and Imaging

    1. Front Matter
      Pages 1-1
    2. Eva Corey, Robert L. Vessella
      Pages 3-31
    3. Milton W. Datta, André A. Kajdacsy-Balla
      Pages 49-62
    4. Jack A. Schalken
      Pages 63-72
    5. Leland W. K. Chung, Wen-Chin Huang, Shian-Ying Sung, Daqing Wu, Valerie Odero-Marah, Haiyen E. Zhau
      Pages 73-86
    6. Helmut Klocker, Iris E. Eder, Barbara Comuzzi, Georg Bartsch, Zoran Culig
      Pages 87-105
    7. Mohini Lutchman, Keith R. Solomon, Michael R. Freeman
      Pages 119-137
    8. Juan Antonio, Xiong Li, Thomas A. Gardner, Chinghai Kao
      Pages 139-163
    9. Chung Lee, Ali Shah, Victoria Liu, Irwin Park, Larry Wong, Xuemei Huang et al.
      Pages 165-174
    10. Meera Iyer, Sanjiv S. Gambhir
      Pages 193-229
    11. Xiaohu Gao, Yun Xing, Leland W. K. Chung, Shuming Nie
      Pages 231-244
  3. Genetics

    1. Front Matter
      Pages 245-245
    2. Scott A. Tomlins, Arul M. Chinnaiyan
      Pages 247-267
    3. Kati P. Porkka, Tapio Visakorpi
      Pages 269-283
    4. William G. Nelson, Srinivasan Yegnasubramanian, Patrick J. Bastian, Masashi Nakayama, Angelo M. De Marzo
      Pages 301-315
  4. Therapeutics

    1. Front Matter
      Pages 353-353
    2. James L. Mohler
      Pages 355-376
    3. Danny Y. Song, Theodore L. DeWeese
      Pages 377-396
    4. Anoop M. Meraney, Warren W. D. Heston
      Pages 397-410
    5. Madeleine S. Q. Kortenhorst, Michael A. Carducci, Shabana Shabbeer
      Pages 411-443
    6. Supriya G. Mohile, Daniel P. Petrylak
      Pages 445-462
    7. Young E. Whang, Daniel J. George
      Pages 475-486
  5. Back Matter
    Pages 497-508

About this book


Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations and advances in prostate cancer and may be used as a rapid reference text for readers.

The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth.

Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, provides readers with a general reference for prostate cancer from prevention to therapy and will be of value to clinicians, scientists, and administrators who strive to solve the cancer problem.


cancer carcinogenesis cell chemotherapy clinical trial gene therapy genetics genomics hormones imaging immunotherapy molecular imaging mortality prostate cancer radiotherapy

Editors and affiliations

  • Leland W. K. Chung
    • 1
  • William B. Isaacs
    • 2
  • Jonathan W. Simons
    • 3
  1. 1.Emory University School of MedicineAtlanta
  2. 2.Johns Hopkins University School of MedicineBaltimore
  3. 3.Prostate Cancer FoundationSanta Monica

Bibliographic information

  • DOI
  • Copyright Information Humana Press Inc. 2007
  • Publisher Name Humana Press
  • eBook Packages Medicine
  • Print ISBN 978-1-58829-696-2
  • Online ISBN 978-1-59745-224-3
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals