Pharmacogenomics in Drug Discovery and Development

From Bench to Bedside

  • Qing Yan

Part of the Methods in Molecular Biology™ book series (MIMB, volume 448)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Tristan M. Sissung, Erin R. Gardner, Rui Gao, William D. Figg
    Pages 41-62
  3. Miles D. Thompson, David E. C. Cole, Pedro A. Jose
    Pages 77-107
  4. Miles D. Thompson, Maire E. Percy, W. McIntyre Burnham, David E. C. Cole
    Pages 109-137
  5. Miles D. Thompson, Katherine A. Siminovitch, David E. C. Cole
    Pages 139-185
  6. Hamid Mostafavi Abdolmaleky, Cassandra L. Smith, Jin-Rong Zhou, Sam Thiagalingam
    Pages 187-212
  7. Ramón Cacabelos
    Pages 213-357
  8. Gregory A. Hawkins, Stephen P. Peters
    Pages 359-378
  9. Michael Camilleri, Yuri A. Saito
    Pages 395-412
  10. Prabha Ranganathan
    Pages 413-435
  11. Sharon Marsh
    Pages 437-446
  12. Back Matter
    Pages 481-487

About this book


Since each human is genetically distinctive, responding differently to disease-causing factors as well as drugs, the field pharmacogenomics arose to develop personalized medicine, or medicine that deals with the complexity of the human body.  In Pharmacogenomics in Drug Discovery and Development, leading experts present methodical, state-of-the-art contributions covering topics from individual molecules to systemic diseases, examining both fundamental concepts and advanced technologies.  Divided into three sections, the volume begins by exploring cutting-edge technologies used to pursue systems-based pharmacogenomics, followed by extensive chapters on gene-drug interactions and the use of pharmacogenomics in therapeutics of diseases. Although not in standard Methods in Molecular Biology™ series format, the book retains the practicality and usefulness of the highly successful series.

Comprehensive and up-to-date, Pharmacogenomics in Drug Discovery and Development is an ideal volume for scientists striving to transform disease treatment into disease prevention.


Asthma Biomarker genes and pathways Biomarkers Drug response phenotypes Gene-drug interactions Genotypes Personalized medicine Therapeutics of disease dopamine

Editors and affiliations

  • Qing Yan
    • 1
  1. 1.PharmTaoSanta ClaraUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-887-4
  • Online ISBN 978-1-59745-205-2
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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