© 2008

Antiangiogenic Agents in Cancer Therapy

  • Beverly A. Teicher
  • Lee M. Ellis
  • Current perspectives on state-of-the-art therapies

  • Contains chapters specific to angiogenesis and antiangiogenic treatment of many malignant diseases


Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages I-XVIII
  2. Basic Biology of Angiogenesis

    1. Front Matter
      Pages 1-1
    2. Mark W. Dewhirst, Yiting Cao, Gordana Vlahovic
      Pages 27-47
    3. Aparna R. Aiyer, Judith A. Varner
      Pages 49-71
    4. Andrew C. Dudley, Michael Klagsbrun
      Pages 73-84
    5. Sunyoung Lee, M. Luisa Iruela-Arispe
      Pages 85-97
    6. Rebecca G. Bagley
      Pages 99-115
    7. Chunhua Lu, Anil K. Sood
      Pages 117-132
    8. Beverly A. Teicher
      Pages 133-153
    9. Michael P. Keane, John A. Belperio, Robert M. Strieter
      Pages 155-170
    10. Hanako Kobayashi, Laura M. DeBusk, P. Charles Lin
      Pages 171-187
    11. Sanjeeva P. Kalva, Saravanan Namasivayam, Dushyant Vasuedeo Sahani
      Pages 189-203
    12. Yineng Fu, Janice A. Nagy, Ann M. Dvorak, Harold F. Dvorak
      Pages 205-224
    13. Bronislaw Pytowski
      Pages 225-241
  3. Translational Research in Tumor Angiogenesis

    1. Front Matter
      Pages 243-243
    2. Arindel S.R. Maharaj, Patricia A. D’Amore
      Pages 245-259
    3. Rakesh K. Jain, Tracy T. Batchelor, Dan G. Duda, Christopher G. Willett
      Pages 261-276
    4. Robert S. Kerbel, U. Emmenegger, S. Man, R. Munoz, C. Folkins, Y. Shaked
      Pages 277-296
    5. Dietmar W. Siemann, Michael R. Horsman
      Pages 297-310

About this book


Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer.  Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. 

Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.


CNS Chemokine angiogenesis cancer cancer therapy carcinoma cell chemotherapy clinical trial imaging oncology pathology radiotherapy research tumor

Editors and affiliations

  • Beverly A. Teicher
    • 1
  • Lee M. Ellis
    • 2
  1. 1.Genzyme CorporationFramingham
  2. 2.M. D. Anderson Cancer CenterThe University of TexasHouston

Bibliographic information

  • Book Title Antiangiogenic Agents in Cancer Therapy
  • Editors Beverly A. Teicher
    Lee M. Ellis
  • Series Title Cancer Drug Discovery and Development
  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-870-6
  • Softcover ISBN 978-1-4939-5628-9
  • eBook ISBN 978-1-59745-184-0
  • Edition Number 2
  • Number of Pages XVIII, 559
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cancer Research
    Surgical Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology
Consumer Packaged Goods


From the reviews of the second edition:

"This is a second edition of a well-accepted text on angiogenesis and antiangiogenic agents, particularly on their use in cancer therapy. In addition to the editors, a large number of outstanding investigators have contributed to this book. … This edition is highly recommended to all of those involved in research or the clinical practice of oncology." (Julian L. Ambrus and Clara M. Ambrus, The Journal of Medicine, March, 2008)