Post-Transcriptional Gene Regulation

  • Jeffrey Wilusz

Part of the Methods In Molecular Biology™ book series (MIMB, volume 419)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Bioinformatics

    1. Front Matter
      Pages 1-1
    2. Francis Doyle, Christopher Zaleski, Ajish D. George, Erin K. Stenson, Adele Ricciardi, Scott A. Tenenbaum
      Pages 39-52
  3. Fundamental Aspects of the Study of RNA Biology

    1. Front Matter
      Pages 51-51
    2. Elizabeth E. Regulski, Ronald R. Breaker
      Pages 53-67
    3. Timothy E. Baroni, Sridar V. Chittur, Ajish D. George, Scott A. Tenenbaum
      Pages 93-108
    4. Sara Tombelli, Maria Minunni, Marco Mascini
      Pages 109-119
    5. Sandra L. Clement, Jens Lykke-Andersen
      Pages 121-133
    6. Gusti M. Zeiner, Michael D. Cleary, Ashley E. Fouts, Christopher D. Meiring, Edward S. Mocarski, John C. Boothroyd
      Pages 135-146
  4. Techniques for Specific Aspects of RNA Biology

    1. Front Matter
      Pages 159-159
    2. Julian P. Venables
      Pages 161-170
    3. Lisa K. Hague, Tyra Hall-Pogar, Carol S. Lutz
      Pages 171-185
    4. Samuel B. Stephens, Rebecca D. Dodd, Rachel S. Lerner, Brook M. Pyhtila, Christopher V. Nicchitta
      Pages 197-214
    5. Jing Peng, Elizabeth L. Murray, Daniel R. Schoenberg
      Pages 215-230
    6. Elizabeth L. Murray, Daniel R. Schoenberg
      Pages 259-276
    7. Kevin Sokoloski, John R. Anderson, Jeffrey Wilusz
      Pages 277-288
    8. Angie Cheng, Charles L. Johnson, Lance P. Ford
      Pages 303-316
  5. Back Matter
    Pages 317-318

About this book


In Post-Transcriptional Gene Regulation, renowned authors present current technical approaches to most aspects of post-transcriptional control and provide a useful and versatile laboratory bench resource. With chapters split into sections covering bioinformatics, fundamental aspects of the study of RNA biology, and techniques for specific aspects of RNA biology, the expert authors have filled the book with invaluable tricks of the trade, perfected in their state-of-the-art laboratories.

This new volume from the Methods in Molecular Biology series is convinently divided into three sections. The first section presents a series of bioinformatic approaches to address the use of RNA databases and algorithms to the study of post-transcriptional regulation involving untranslated regions of transcripts. In the second section, a series of methods applicable to fundamental issues in mRNA biology are presented. These include RNA structure/function, mRNP analysis and novel methods for mRNA labeling and isolation. The third section of this volume presents methodologies to study particular aspects of post-transcriptional control. This section includes methods for the study of alternative splicing and 3’ end processing, mRNA localization, mRNA translation, mRNA stability and si/miRNA regulation. Collectively, Post-Transcriptional Gene Regulation provides the reader with a useful and versatile laboratory bench resource that will become an essential reference in the field.


Bioinformatics Microarray PCR Post-Transcriptional control RNA biology Translation algorithms biology databases gene expression genes genome miRNAs molecular biology transcription

Editors and affiliations

  • Jeffrey Wilusz
    • 1
  1. 1.Department of Microbiology, Immunology and PathologyColorado State UniversityFort CollinsUSA

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-783-9
  • Online ISBN 978-1-59745-033-1
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site
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