© 2007

Essentials of Restenosis

For the Interventional Cardiologist

  • Henricus J. Duckers
  • Elizabeth G. Nabel
  • Patrick W. Serruys
  • Gold-standard reference on the treatment of restenosis for interventional cardiologists

  • Produced by leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, and Thomas Luscher


Part of the Contemporary Cardiology book series (CONCARD)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Pathophysiology and Diagnosis

    1. Front Matter
      Pages 1-1
    2. Henricus J. Duckers, Caroline Cheng, Dennie Tempel, Patrick W. Serruys
      Pages 3-5
    3. Randolph L. Geary, Alexander W. Clowes
      Pages 7-28
    4. Ganesh Manoharan, Giedrius Davidavicius, William Wijns
      Pages 29-46
    5. Renu Virmani, Frank D. Kolodgie, Aloke V. Finn, Herman K. Gold
      Pages 47-58
    6. Attila Thury, Jolanda J. Wentzel, Frank J. H. Gijsen, Johan C. H. Schuurbiers, Rob Krams, Pim J. de Feyter et al.
      Pages 59-83
    7. Arturo G. Touchard, Robert S. Schwartz
      Pages 131-150
  3. Genetic Basis of Restenosis

    1. Front Matter
      Pages 151-151
    2. Thomas W. Johnson, Karl R. Karsch
      Pages 153-165
    3. Dietlind Zohlnhöfer, Franz-Josef Neumann
      Pages 167-173
    4. Santhi K. Ganesh, Elizabeth G. Nabel
      Pages 175-183
    5. Andrew Wragg, Manfred Boehm
      Pages 199-212
    6. Gerard Pasterkamp, Bradley H. Strauss, Dominique de Kleijn
      Pages 213-225
    7. Alexey Kuroedov, Francesco Cosentino, Felix C. Tanner, F. Lüscher
      Pages 227-243
  4. Diagnosis of Restenosis

    1. Front Matter
      Pages 245-245
    2. Volker Klauss, Nico H. J. Pijls
      Pages 247-256
    3. Giedrius Davidavicius, Ganesh Manoharan, William Wijns
      Pages 257-275

About this book


Essentials of Restenosis provides the practicing cardiologists and biologists an elaborate review of the current advances in the field. Authors explore the process of restenosis from bench to bedside, encompassing in equal detail the newest scientific findings of the biological mechanisms as well as the progression in development of diagnostics and treatments. The volume also provides the reader with a basic understanding of the biological process and the latest diagnostics and treatments of the disease, with an up-to-date detailed discussion of the most important recent findings.

Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists. Thorough chapters discuss the current understanding on the pathophysiology, molecular and genetic base, and methods of diagnosis of restenosis, and present the current state-of-the-art management, including pharmacotherapy and interventional percutaneous approaches using brachytherapy, gene therapy and drug eluting stent technology.

All this makes Essentials of Restenosis an excellent handbook for introducing new intervention cardiologists, vascular biologists, and medical students into the subject. This text provides the reader with a complete overview of the basic and applied knowledge of restenosis, leading to better insight and decision-making in clinical practice.


Stent anatomy computed tomography (CT) coronary imaging diagnosis diagnostics gene therapy immune system magnetic resonance magnetic resonance imaging magnetic resonance imaging (MRI) pathophysiology physiology tomography vascular disease

Editors and affiliations

  • Henricus J. Duckers
    • 1
  • Elizabeth G. Nabel
    • 2
  • Patrick W. Serruys
    • 1
  1. 1.Thoraxcenter, Erasmus Medical Center RotterdamRotterdamThe Netherlands
  2. 2.The Nabel Lab, Genome Technology Branch, NHGRI Division of Intramural Research, National Heart, Lung, and Blood InstituteNational Institutes of HealthBethesda

Bibliographic information

  • Book Title Essentials of Restenosis
  • Book Subtitle For the Interventional Cardiologist
  • Editors Henricus J. Duckers
    Elizabeth G. Nabel
    Patrick W. Serruys
  • Series Title Contemporary Cardiology
  • DOI
  • Copyright Information Humana Press Inc. 2007
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-491-3
  • Softcover ISBN 978-1-4939-6110-8
  • eBook ISBN 978-1-59745-001-0
  • Edition Number 1
  • Number of Pages XXX, 458
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cardiology
    Vascular Surgery
    Internal Medicine
    Interventional Radiology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


From the reviews:

"This is a comprehensive review of the problem of restenosis, from the basic science to clinical management. … The audience includes interventional cardiology fellows and interventional cardiologists. The book describes the difficulties that cardiologists face trying to prevent and manage restenosis. … Each chapter includes extensive references. This is a complete, state-of-the-art review of restenosis, covering all aspects of restenosis from pathophysiology to therapeutic management. The authors are leaders in interventional cardiology with extensive clinical experience in the field." (Adriana Maria Rosario, Doody’s Review Service, December, 2007)

"A multiauthored, comprehensive compendium of virtually all aspects of the restenotic process after balloon- or stent-induced arterial injury. ... The text is written by a blueribbon panel of authors who provide an in-depth coverage of the topics. Many of the clinical chapters offer an excellent historical perspective on the problem of restenotis. ... Recommended Readership: Interventional (clinical and research) cardiologists and interventional fellows." (John F. Bresnahan, Mayo Clinic Proceedings, Vol. 83 (4), April, 2008)