© 2005

Portal Hypertension

Pathobiology, Evaluation, and Treatment

  • Arun J. Sanyal
  • Vijay H. Shah

Part of the Clinical Gastroenterology book series (CG)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Historical Perspective

    1. Front Matter
      Pages 1-1
    2. Adrian Reuben, Roberto J. Groszmann
      Pages 3-11
  3. Pathobiology and Experimental Progress in Portal Hypertension

  4. Methodology to Assess Portal Hypertension in Humans

    1. Front Matter
      Pages 127-127
    2. G. Pomier-Layrargues, P.-Michel Huet
      Pages 129-144
  5. Natural History and Treatment of Esophageal Varices

    1. Front Matter
      Pages 165-165
    2. Juan G. Abraldes, Jaime Bosch
      Pages 167-181
    3. Norman D. Grace, Richard S. Tilson
      Pages 199-219

About this book


Although the past several years have seen tremendous progress in both the understanding and clinical management of portal hypertension-a major complication of cirrhosis-many new therapies and pathogenic principles are now emerging that will lead to vastly improved therapeutic approaches in the years to come. In Portal Hypertension: Pathobiology, Evaluation, and Treatment, internationally renowned investigators and clinicians discuss the latest findings on key scientific topics and review the evaluation and management of portal hypertension in the clinic. Writing in an easy-to-read style, the authors review its pathobiology, the progress being made in its experimental understanding, the methodologies to assess it in humans, the treatment of its complications (esophageal varices, ascites, and hepatorenal syndrome), and its treatment in special circumstances (during pregnancy, in children, or when the portal vein is blocked). They also provide in-depth coverage of the pros and cons of the various therapeutic choices available to the clinician managing patients with complicated portal hypertension.
State-of-the-art and readily accessible, Portal Hypertension: Pathobiology, Evaluation, and Treatment provides both an authoritative reference for all gastroenterologists and an indispensable resource for all physicians treating liver disease, particularly in a tertiary care setting.


Ascites Esophageal varices Hepatic encephalopathy Hepatorenal syndrome Hyponatremia Neovascularization Portal vein thrombosis Stent Vasodilation hypertension

Editors and affiliations

  • Arun J. Sanyal
    • 1
  • Vijay H. Shah
    • 2
  1. 1.Division of GastroenterologyVirginia Commonwealth Medical CenterRichmond
  2. 2.GI Research UnitMayo ClinicRochester

Bibliographic information

  • Book Title Portal Hypertension
  • Book Subtitle Pathobiology, Evaluation, and Treatment
  • Editors Arun J. Sanyal
    Vijay H. Shah
  • Series Title Clinical Gastroenterology
  • DOI
  • Copyright Information Humana Press Inc. 2005
  • Publisher Name Humana Press
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-58829-386-2
  • Softcover ISBN 978-1-61737-535-4
  • eBook ISBN 978-1-59259-885-4
  • Edition Number 1
  • Number of Pages , 528
  • Number of Illustrations 125 b/w illustrations, 1 illustrations in colour
  • Topics Hepatology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Internal Medicine & Dermatology


"...truly insightful...the book beautifully builds upon the molecular and biological machinery into an enhanced clinical understanding of portal hypertension complete with the most up-to-date treatment options." - Practical Gastroenterology

"...provides exceptional reading material encompassing a broad range of topics on basic and clinical aspecgts of portal hypertension...strongly recommended to researchers, practicing physicians, trainees, and others with an interest in this subject." Weighted Numerical Score: 96 - 4 Stars! - Doody's Health Science Book Review Journal

"...the ideal guide for those who want to deal with the clinical problems of portal hypertension in a modern and effective way." - Digestive and Liver Disease