Management of Prostate Cancer

  • Eric A. Klein

Part of the Current Clinical Urology book series (CCU)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Howard S. Levin
    Pages 1-17
  3. Elizabeth A. Platz, Philip W. Kantoff, Edward Giovannucci
    Pages 19-45
  4. Meena Augustus, Judd W. Moul, Shiv Srivastava
    Pages 47-70
  5. Ian M. Thompson, John Foley
    Pages 71-85
  6. Christopher A. Haas, Martin I. Resnick
    Pages 87-101
  7. Michael O. Koch, Joseph A. Smith, David A. Miller, Roxelyn G. Baumgartner, Nancy Wells
    Pages 117-131
  8. Eric A. Klein, Mark R. Licht, Faiyaaz Jhaveri
    Pages 133-158
  9. Patrick Kupelian
    Pages 159-181
  10. David F. Penson, Mark S. Litwin
    Pages 183-198
  11. Milton M. Lakin, Leslie R. Schover
    Pages 211-221
  12. Craig D. Zippe, Anurag W. Kedia
    Pages 223-243
  13. Marcos V. Tefilli, Edward L. Gheiler, J. Edson Pontes
    Pages 245-263
  14. Ali Ziada, Mark Rosenblum, E. David Crawford
    Pages 265-288
  15. Jeffrey M. Kamradt, Kenneth J. Pienta
    Pages 289-303
  16. Michael G. Rashid, Martin G. Sanda
    Pages 317-336
  17. Apoorva R. Vashi, James E. Montie
    Pages 337-351
  18. Back Matter
    Pages 363-372

About this book


Prostate cancer remains the most common malignant tumor in elderly men. The National Cancer Institute estimated 210,000 new cases of prostate cancer in 1997. There is, however, no means of documenting the true incidence of prostate cancer because of the difficulty in detecting all cases. Even using yearly rectal exams, PSA determinations, and ultrasound-guided prostate biopsies, many cases are missed. Suffice it to say that prostate cancer is a widely occurring disease in men and early detection and treatment are extremely important. When I trained in Urology under Dr. Reed Nesbit at the University of Michigan from 1956 to 1959, the diagnosis of prostate cancer was made by a rectal examination and an acid phosphatase determination. If there was a small nodule in the prostate, then an anterior-posterior X-ray of the pelvis was obtained to look for possible bony metastases. If the acid phosphatase was normal and there was no evidence ofa bony metastasis, the prostate was exposed through the perineal approach and a biopsy of the nodule was obtained and sent for frozen section to Pathology to determine if it was indeed a cancer of the prostate. If the biopsy came back positive, the surgeon then proceeded to do a radical perineal prostatectomy. In those days, we usually did eight to ten radical perineal prostatectomies yearly. Many times the nodule that was biopsied was benign, and the incision was simply closed.


biopsy cancer metastasis pathology prostate cancer prostatectomy tumor ultrasound urology

Editors and affiliations

  • Eric A. Klein
    • 1
  1. 1.Section of Urologic Oncology, Department of UrologyCleveland Clinic FoundationClevelandUSA

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