© 2004

Handbook of Drug Interactions

A Clinical and Forensic Guide

  • Ashraf Mozayani
  • Lionel P. Raymon

Part of the Forensic Science and Medicine book series (FSM)

Table of contents

  1. Front Matter
    Pages i-x
  2. Central Nervous System Drugs

    1. Front Matter
      Pages 1-1
    2. David E. Moody
      Pages 3-88
    3. Nathan L. Kanous II, Barry E. Gidal
      Pages 89-122
    4. Seyed-Adel Moallem, Kia Balali-Mood, Mahdi Balali-Mood
      Pages 123-148
    5. Mojdeh Mozayani, Ashraf Mozayani
      Pages 175-185
    6. Michael Welner
      Pages 187-215
  3. Cardiovascular Drugs

    1. Front Matter
      Pages 217-217
    2. Johann Auer
      Pages 219-292
  4. Antibiotics

    1. Front Matter
      Pages 293-293
    2. Amanda J. Jenkins, Jimmie L. Valentine
      Pages 295-318
  5. Nonsteroidal Antiinflammatory Drugs

    1. Front Matter
      Pages 335-335
    2. Imad K. Abukhalaf, Daniel A. von Deutsch, Mohamed A. Bayorh, Robin R. Socci
      Pages 337-376
  6. Environmental and Social Pharmacology

    1. Front Matter
      Pages 377-377
    2. Shahla M. Wunderlich
      Pages 379-393
    3. A. Wayne Jones
      Pages 395-462
    4. Edward J. Cone, Reginald V. Fant, Jack E. Henningfield
      Pages 463-492
    5. Daniel A. von Deutsch, Imad K. Abukhalaf, Robin R. Socci
      Pages 493-596

About this book


Drug interactions and adverse drug effects are responsible for the hospitalization and extended hospitalization of more than 100,000 Americans annually, not to mention a significant number of deaths. In Handbook of Drug Interactions: A Clinical and Forensic Guide, leading drug experts from pharmacology, toxicology, medicine, nutrition, and law have compiled a concise record of the known interactions of the most commonly prescribed drugs, as well as their interaction with nonprescription compounds. The agents covered include CNS drugs, cardiovascular drugs, antibiotics, and NSAIDs. The authors review the pharmacology, pharmacodynamics, pharmacokinetics, chemistry, metabolism, epidemiological occurrences, adverse reactions, and significant interactions for each class of drugs. Where necessary, they also consider forensic factors and implications for criminal law, malpractice, and tort litigation. Environmental and social pharmacological issues are also addressed in chapters on food and alcohol drug interactions, nicotine and tobacco, and anabolic doping agents. Individual chapters are devoted to drug interaction litigation and the role of psychotropic medications in crime. A detailed index provides rapid access to the book's extensive information on potential interactions.
Comprehensive and thorough, Handbook of Drug Interactions: A Clinical and Forensic Guide provides physicians with all the information needed to avoid prescribing drugs with undesirable interactions, and those active in clinical chemistry and laboratory medicine with all the data necessary to interpret possible interactions between drugs found simultaneously in patient samples.


AIDS CNS HIV chemistry cytochrome P450 drug kinetics metabolism opioid pharmacodynamics pharmacokinetics serotonin

Editors and affiliations

  • Ashraf Mozayani
    • 1
  • Lionel P. Raymon
    • 2
  1. 1.Harris County Medical Examiner OfficeHoustonUSA
  2. 2.University of Miami School of MedicineMiamiUSA

Bibliographic information

  • Book Title Handbook of Drug Interactions
  • Book Subtitle A Clinical and Forensic Guide
  • Editors Ashraf Mozayani
    Lionel Raymon
  • Series Title Forensic Science and Medicine
  • DOI
  • Copyright Information Humana Press 2004
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-1-58829-211-7
  • Softcover ISBN 978-1-61737-424-1
  • eBook ISBN 978-1-59259-654-6
  • Edition Number 1
  • Number of Pages X, 663
  • Number of Illustrations 36 b/w illustrations, 0 illustrations in colour
  • Topics Forensic Medicine
  • Buy this book on publisher's site
Industry Sectors


"This book offers a comprehensive guide to drug interactions and has particular utility in both the educational and clinical environments. In the academic arena it offers some insights to the legal implications not discussed on other resources. This book would also make a valuable addition to the clinical library. . .It is organized by drug class, with the major classes represented, including CNS drugs, cardiovascular agents, antibiotics and nonsteroidal anti-inflammatory agents. A unique section covers environmental and social pharmacology issues with regards to drug interactions, including the influence of food, alcohol, tobacco, and anabolic agents. One of the more unique features of the book are the two final chapters that address litigation regarding drug interactions and psychotropic medications and crime. Tables are extensively and wisely used throughout to present large amounts of drug interaction data in an appropriate synopsis for quick reference. Illustrations of chemical structures to elucidate pharmacological interactions are appropriately used." -Doody's Health Sciences Book Review Journal

"The book is effective in gathering information about several classes of drugs in one volume...Recommended." -E-STREAMS

"...a welcome addition...I would recommend this text as a useful reference to students, researchers and physicians alike." - BTS Newsletter