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Stem Cells Handbook

  • Book
  • © 2004

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Editors:
  1. Stewart Sell

    1. Wadsworth Center and Ordway Research Institute, Albany, USA

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Table of contents (43 chapters)

  1. Development of the Cardiovascular System in Embryoid Bodies Derived from Embryonic Stem Cells

    • Heinrich Sauer, Maria Wartenberg, Agapios Sachinidis, Jürgen Hescheler
    Pages 229-238

  2. Transcription Factors, Growth Factors, and Signal Cascades Capable of Priming Cardiogenesis

    • Agapios Sachinidis, Heinrich Sauer, Maria Wartenberg, Jürgen Hescheler
    Pages 239-249

  3. Strategies Using Cell Therapy to Induce Cardiomyocyte Regeneration in Adults with Heart Disease

    • Silviu Itescu
    Pages 251-258

  4. Generation and Stem Cell Repair of Cardiac Tissue

    • Kathyjo A. Jackson, Margaret A. Goodell
    Pages 259-266

  5. Stem Cells In Kidney Morphogenesis

    • Emma M. A. Ball, Gail P. Risbridger
    Pages 267-275

  6. Nephroblastoma

    • Alan O. Perantoni
    Pages 277-287

  7. Stem Cells in Nonmelanoma Skin Cancer

    • Wendy C. Weinberg, Stuart H. Yuspa
    Pages 289-296

  8. The Stem Cell Plasticity of Aggressive Melanoma Tumor Cells

    • Mary J. C. Hendrix, Elisabeth A. Seftor, Paul S. Meltzer, Angela R. Hess, Lynn M. Gruman, Brian J. Nickoloff et al.
    Pages 297-306

  9. Stem Cells in Glandular Organs

    • Karin Williams, Simon W. Hayward
    Pages 307-315

  10. Gastrointestinal Stem Cells

    • Sherif M. Karam
    Pages 317-328

  11. Stem Cell Origin of Cell Lineages, Proliferative Units, and Cancer in the Gastrointestinal Tract

    • Mairi Brittan, Nicholas A. Wright
    Pages 329-343

  12. Specification of Liver from Embryonic Endoderm

    • Hideyuki Yoshitomi, Kenneth S. Zaret
    Pages 345-352

  13. Animal Models for Assessing the Contribution of Stem Cells to Liver Development

    • Douglas C. Hixson
    Pages 353-366

  14. Normal Liver Progenitor Cells in Culture

    • Katherine S. Koch, Hyam L. Leffert
    Pages 367-384

  15. Permanent Lines of Stem Cells from the Liver

    • Hélène Strick-Marchand, Mary C. Weiss
    Pages 385-395

  16. Biology of Human Liver Stem Cells

    • Alastair J. Strain, Sarbjit S. Nijjar, Heather A. Crosby
    Pages 397-407

  17. Transplantation of Hepatic Stem Cells and Potential Applications for Cell Therapy

    • Sanjeev Gupta, Jae-Jin Cho
    Pages 409-416

  18. Plasticity of Adult-Derived Pancreatic Stem Cells

    • Ammon B. Peck, Vijayakumar K. Ramiya
    Pages 417-427

  19. Islet Cells

    • Luc Bouwens
    Pages 429-436

  20. Mammary Epithelial Stem Cells

    • Gilbert H. Smith
    Pages 437-443
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Keywords

About this book

The power of stem cells for tissue development, regeneration, and renewal has been well known by embryologists and developmental biologists for many years. Those presently active in research in the stem cell field owe much to previous work by embryologists and cancer researchers for their insights into what stem cells can do. In the last 4- 5 years, the rapid expansion of the concept of adult tissue stem cells as pluripotent progenitors for various tissues has led to an even greater appreciation of the power of stem cells. The demonstration that both embryonic and adult tissue stem cells have the ability to produce progenitor cells for tissue renewal has opened vast possibilities for treatment of congenital deficiency diseases as well as for regeneration of damaged tissues. Older concepts of determination leading to loss of potential during differentiation of adult tissues are being replaced by newer ideas that cells with multiple potential exist in different forms in various adult organs and that cells thought to be restricted to differentiation to one cell type may be able to "transdifferentiate" into other tissue cell types. Thus, the concept of "embryonic rests" in adult tissues, hypothesized to be the cellular origin of cancer by Durante and Conheim in the 1870s, now can be expanded to include survival of pluripotential embryonic-like stem cells in adult tissues.

Reviews

"Truly outstanding descriptions of the fields of early mammalian development, DNA methylation, neural stem cell biology, and imaging technologies help round the reader's knowledge through the use of perspicuous language and concepts." - Developmental Cell

Editors and Affiliations

  • Wadsworth Center and Ordway Research Institute, Albany, USA

    Stewart Sell

Bibliographic Information

  • Book Title: Stem Cells Handbook

  • Editors: Stewart Sell

  • DOI: https://doi.org/10.1007/978-1-59259-411-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 2004

  • Softcover ISBN: 978-1-61737-367-1Published: 09 December 2010

  • eBook ISBN: 978-1-59259-411-5Published: 22 October 2003

  • Edition Number: 1

  • Number of Pages: XIII, 509

  • Number of Illustrations: 229 b/w illustrations, 22 illustrations in colour

  • Topics: Human Genetics

  • Industry Sectors: Biotechnology, Pharma

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