Expression Profiling of Human Tumors

Diagnostic and Research Applications

  • Marc Ladanyi
  • William L. Gerald

Table of contents

  1. Front Matter
    Pages i-x
  2. Introduction

    1. Front Matter
      Pages 1-1
  3. Technical Aspects

    1. Front Matter
      Pages 9-9
    2. Paul S. Meltzer
      Pages 11-21
    3. Marina Chicurel, Dennise Dalma-Weiszhausz
      Pages 23-46
    4. Cyrus V. Hedvat
      Pages 61-72
    5. Pablo Tamayo, Sridhar Ramaswamy
      Pages 73-101
    6. Stephen J. Qualman, Jay Bowen, Sandra Brewer-Swartz, Mary France
      Pages 103-117
  4. Applications

    1. Front Matter
      Pages 119-119
    2. Irene L. Andrulis, Nalan Gokgoz, Shelley B. Bull
      Pages 121-145
    3. Daniel A. Notterman, Carrie J. Shawber, Wei Liu
      Pages 147-171
    4. William L. Gerald
      Pages 173-197
    5. Arindam Bhattacharjee, Matthew Meyerson
      Pages 199-217
    6. Marta Sánchez-Carbayo, Carlos Cordon-Cardo
      Pages 219-233
    7. Christine A. Iacobuzio-Donahue, Ralph H. Hruban
      Pages 257-275
    8. Garret M. Hampton
      Pages 277-294
    9. Javed Khan, Marc Ladanyi
      Pages 295-304
    10. Sabine C. Linn, Rob B. West, Matt van de Rijn
      Pages 305-327
    11. Wing C. Chan, Louis M. Staudt
      Pages 329-344
    12. Meena K. Tanwar, Eric C. Holland
      Pages 345-357
    13. Deborah Schofield, Daniel Wai, Timothy J. Triche
      Pages 359-391
  5. Back Matter
    Pages 393-399

About this book


Global gene expression profiling is a new and comprehensive approach to the investigation of tumor biology that has the potential to sharply alter the future of cancer research, diagnostic pathology, and clinical oncology. In Expression Profiling of Human Tumors: Diagnostic and Research Applications, over 20 leading investigators offer the first thorough review of the application of this novel technology to human tumors. The authors focus on the analysis of human tissue samples for a variety of cancers, including breast, colorectal, lung, renal, ovarian, bone, and brain tumors, among others. For each cancer type, the authors assess the potential of the approach in reaching more precise diagnoses, as well as in the identification of prognostic markers, therapeutic targets, and gene expression patterns that accurately predict therapeutic response. A section on the technology and its novel analytical methods explains both the theory and practice of comprehensive gene expression profiling
Timely and topical, Expression Profiling of Human Tumors: Diagnostic and Research Applications provides every cancer researcher, oncologist, pathologist, and cancer surgeon an essential introduction to the most promising high-throughput investigative approach in molecular biology today-a technology that is already dramatically reshaping the future of cancer research, diagnostic pathology, and clinical oncology.


DNA brain tumor brain tumors cancer carcinoma cell classification genomics molecular biology oncology pathology renal cell carcinoma tissue tumor

Editors and affiliations

  • Marc Ladanyi
    • 1
  • William L. Gerald
    • 1
  1. 1.Department of PathologyMemorial Sloan-Kettering Cancer CenterNew YorkUSA

Bibliographic information

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