Handbook of Industrial Cell Culture

Mammalian, Microbial, and Plant Cells

  • Victor A. Vinci
  • Sarad R. Parekh

Table of contents

  1. Front Matter
    Pages i-x
  2. Mammalian Cell Culture

    1. Front Matter
      Pages 1-1
    2. Peter P. Mueller, Dagmar Wirth, Jacqueline Unsinger, Hansjörg Hauser
      Pages 21-49
    3. William H. Velander, Kevin E. van Cott
      Pages 51-67
    4. Steven Rose, Thomas Black, Divakar Ramakrishnan
      Pages 69-103
  3. Microbial Cell Culture

    1. Front Matter
      Pages 105-105
    2. Matthew D. Hilton
      Pages 107-136
  4. Plant Cell Culture

    1. Front Matter
      Pages 195-195
    2. Sam Reddy, Ignacio M. Larrinua, Max O. Ruegger, Vipula K. Shukla, Yuejin Sun
      Pages 197-216
    3. Donald J. Merlo
      Pages 217-241
    4. Joseph F. Petolino, Jean L. Roberts, Ponsamuel Jayakumar
      Pages 243-258
  5. Critical Tools for Biotechnology

    1. Front Matter
      Pages 297-297
    2. Gerald W. Becker, Michael D. Knierman, Pavel Shiyanov, John E. Hale
      Pages 321-348
    3. Walter M. van Gulik, Wouter A. van Winden, Joseph J. Heijnen
      Pages 349-392
    4. Jeffrey S. Patrick
      Pages 393-464
    5. Steve del Cardayre, Keith Powell
      Pages 465-481
  6. Back Matter
    Pages 525-536

About this book


The advent of molecular genetics, the progression of transgenic animal and plant methodologies from the laboratory to industrial-scale production, and the development of powerful analytical techniques have each helped standardize the culturing of cells to produce desirable commercial products. In Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells, a diverse team of researchers, technologists, and engineers describe, in simple and practical language, the major current and evolving technologies for improving the biocatalytic capabilities of mammalian, microbial, and plant cells. The authors present state-of-the-art techniques, proven methods, and strategies for industrial screening, cultivation, and scale-up of these cells, and describe their biotechnological and industrial uses. Special emphasis is given to solving the critical issues encountered during the discovery of new drugs, process development, and the manufacture of new and existing compounds. Other topics include recombinant protein expression, bioinformatics, high throughput screening, analytical tools in biotechnology, DNA shuffling, and genomics discovery. The authors all have proven track records in the successful implementation of commercial-scale processes.
Cutting-edge and highly practical, the Handbook of Industrial Cell Culture: Mammalian, Microbial, and Plant Cells not only surveys the best current practices in the art of industrial cell culture across cell types, but also delineates today's evolving technologies with examples of proven practical applications, as well as projections of their future potential.


Expression Fermentation Proteomics bioinformatics biotechnology genetic engineering glycoprotein proteins transgen

Editors and affiliations

  • Victor A. Vinci
    • 1
  • Sarad R. Parekh
    • 2
  1. 1.Eli Lilly and CompanyIndianapolisUSA
  2. 2.Dow AgroSciencesIndianapolisUSA

Bibliographic information

Industry Sectors
Chemical Manufacturing
Consumer Packaged Goods