© 2003

Chemoradiation in Cancer Therapy

  • Hak Choy

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xii
  2. General/Background

    1. Front Matter
      Pages 1-1
    2. Hak Choy, Robert M. MacRae
      Pages 3-22
    3. Muhammad Wasif Saif, Robert B. Diasio
      Pages 23-44
  3. Mechanisms of Interaction of Specific Chemotherapeutic Agents with Radiation

    1. Front Matter
      Pages 45-45
    2. Robert M. MacRae, Hak Choy
      Pages 65-91
    3. Tyvin A. Rich
      Pages 93-103
    4. Jerome Landry, William Blackstock, Robert M. MacRae, Gary Yang, Hak Choy
      Pages 105-126
  4. Clinical Applications

    1. Front Matter
      Pages 127-127
    2. Heather A. Curry, Walter J. Curran Jr.
      Pages 129-144
    3. Julie R. Brahmer, Larry Kleinberg, David S. Ettinger
      Pages 197-213
    4. Arlene Forastiere, Bapsi Chak
      Pages 215-235
    5. Silvia C. Formenti, Matthew Volm
      Pages 237-251
    6. Jason H. Lee, Christopher G. Willett
      Pages 271-289

About this book


The combination of chemotherapeutic drugs and radiation to treat solid tumors has now become a common treatment option in many clinical settings. In Chemoradiation in Cancer Therapy, internationally recognized experts in cancer biology and clinical research review the present status of these multimodality approaches to the management of solid tumors and speculate on possible future strategies for their use. As part of their comprehensive survey, the authors detail applications of combined modality therapy in lung, esophageal, breast, gastric, pancreatic, colon, and rectal cancers. They also show how radiation interacts with such chemotherapeutic agents as the platinum complexes, taxanes, and gemcitabine in the treatment of malignant gliomas, and head and neck cancer. Rounding out the presentation is a review of how to integrate new specific molecular-targeted agents into future multimodality therapy. Here the discussion centers on the antibody for the epidermal growth factor receptor (EGFR), antiangiogenesis agents, farnesyltransferase inhibitors (FTIs), gene therapies, and signaling pathway inhibitors in combination with radiotherapy, and with or without classical chemotherapeutic agents.
State-of-the-art and forward-looking, Chemoradiation in Cancer Therapy offers oncologists a thorough understanding of today's best current and future strategies available for the treatment of solid tumors by chemoradiation therapy.


breast cancer cancer carcinoma chemotherapy gene therapy radiation radiotherapy tumor

Editors and affiliations

  • Hak Choy
    • 1
  1. 1.Department of Radiation OncologyVanderbilt University Medical CenterNashvilleUSA

Bibliographic information

  • Book Title Chemoradiation in Cancer Therapy
  • Editors Hak Choy
  • Series Title Cancer Drug Discovery and Development
  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-1-58829-028-1
  • Softcover ISBN 978-1-61737-313-8
  • eBook ISBN 978-1-59259-325-5
  • Edition Number 1
  • Number of Pages XII, 420
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Oncology
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Oncology & Hematology


"Chemoradiaton in Cancer Therapy offers both clinical and basic oncologists not only a bold synthesis of the rapid and complex advances in new therapeutic modalities, but also highly practical guide to today's best strategies in cancer treatment." -Neoplasma