Type 1 Diabetes

Etiology and Treatment

  • Mark A. Sperling

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Etiology

    1. Front Matter
      Pages 1-1
    2. Janice S. Dorman, Ronald E. LaPorte, Thomas J. Songer
      Pages 3-22
    3. Massimo Pietropaolo, Massimo Trucco
      Pages 23-54
    4. Aristides K. Maniatis, George S. Eisenbarth
      Pages 55-70
    5. Åke Lernmark, Choon Hee Chung
      Pages 71-92
    6. Tiinamaija Tuomi, Jaakko Perheentupa
      Pages 93-114
    7. Nicolai M. Doliba, Franz M. Matschinsky
      Pages 115-144
    8. Philip E. Cryer
      Pages 145-161
    9. Timothy G. Barrett
      Pages 163-179
  3. Treatment of Type 1 Diabetes

    1. Front Matter
      Pages 181-181
    2. Ram K. Menon, Mark A. Sperling
      Pages 183-198
    3. Baiju R. Shah, Bernard Zinman
      Pages 199-213
    4. Jean Betschart Roemer, Linda Siminerio
      Pages 249-260
    5. Christine A. Beebe
      Pages 261-276
  4. Special Management Issues in Type 1 Diabetes

    1. Front Matter
      Pages 277-277
    2. Nadia Tubiana-Rufi, Paul Czernichow
      Pages 279-292
    3. William V. Tamborlane, Elizabeth A. Boland, Margaret Grey
      Pages 293-305
    4. George A. Werther, Fergus J. Cameron, John M. Court
      Pages 307-319
    5. Stephanie A. Amiel, Krystyna Matyka
      Pages 321-343
    6. Erica M. Sommermann, Erin K. Van Meter, Lois Jovanovic
      Pages 345-360
    7. Adrian Vella, Robert A. Rizza
      Pages 361-371
  5. Long-Term Complications of Type 1 Diabetes

    1. Front Matter
      Pages 373-373
    2. Kenya Sakamoto, Michael Brownlee
      Pages 375-392
    3. David Kent, Peter A. Campochiaro
      Pages 393-407
    4. Abhay Vats, Frederick DeRubertis
      Pages 409-436
    5. Eva L. Feldman, Martin J. Stevens, James W. Russell
      Pages 437-461
    6. David L. Steed
      Pages 463-471
    7. Wael Emad Eid, Siripoom McKay, Finnbogi Karlsson, Alan J. Garber
      Pages 473-483
    8. Jean L. Bolognia, Irwin M. Braverman
      Pages 485-499
    9. Nirmal Joshi
      Pages 501-516
    10. R. Paul Robertson
      Pages 517-527
    11. Thierry Berney, Norma Sue Kenyon, Rodolfo Alejandro, Luca Inverardi, Daniel H. Mintz, Camillo Ricordi
      Pages 529-552
    12. Rupangi C. Vasavada, Adolfo Garcia-Ocaña, Karen K. Takane, Ana Cebrian, Juan Carlos Lopez-Talavera, Andrew F. Stewart
      Pages 561-577
  6. Back Matter
    Pages 579-593

About this book


The increasing incidence of diabetes worldwide has prompted a rapid growth in the pace of scientific discovery and clinical understanding of this enigmatic disease. In Type 1 Diabetes: Etiology and Treatment, well-recognized physicians and researchers review the latest thinking about the causes of this condition and the best approaches to treating both its acute and chronic complications. The treatment options discussed range from life-threatening diabetic ketoacidosis to contemporary insulin regimens, from open- and closed-loop insulin delivery devices to modern glucose-sensing mechanisms, as well as such daily life issues as nutrition and education. Also discussed are the management of children under the age of five, the special problems of preadolescents and adolescents, diabetic surgery, and pregnancy, along with the treatment and prevention of the long-term vascular complications that produce coronary artery disease, the loss of limbs, end-stage renal disease, and blindness. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.
Authoritative and up-to-date, Type 1 Diabetes: Etiology and Treatment provides all those caring for diabetic patients with a concise, accessible survey of today's best thinking about the causes, treatment, and management of this complex disease.


Diabetes Insulin Secretion Pancreas growth factor insulin metabolic control

Editors and affiliations

  • Mark A. Sperling
    • 1
    • 2
  1. 1.Department of PediatricsUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.Division of EndocrinologyChildren’s Hospital of PittsburghPittsburghUSA

Bibliographic information

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