Mechanisms and Management

  • Paul L. Wood

Part of the Contemporary Neuroscience book series (CNEURO)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Neuroinflammatory Mechanisms

    1. Front Matter
      Pages 1-1
    2. Paul L. Wood
      Pages 3-27
    3. Christopher C. J. Miller, Steven Ackerley, Janet Brownlees, Andrew J. Grierson, Paul Thornhill
      Pages 89-97
    4. Andrzej R. Glabinski, Richard M. Ransohoff
      Pages 99-115
    5. Kathleen M. K. Boje
      Pages 117-135
    6. Gary L. Wenk, Beatrice Hauss-Wegrzyniak
      Pages 137-150
    7. Gary E. Landreth, Sophia Sundararajan, Michael T. Heneka
      Pages 151-169
  3. Stroke and TBI

    1. Front Matter
      Pages 187-187
    2. Jari Koistinaho, Juha Yrjänheikki
      Pages 189-213
    3. Yvan Gasche, Jean-Christophe Copin, Pak H. Chan
      Pages 237-245
  4. Alzheimer’s Disease

    1. Front Matter
      Pages 247-247
    2. Craig S. Atwood, Mark A. Smith, Ralph N. Martins, Rudolph E. Tanzi, Alex E. Roher, Ashley I. Bush et al.
      Pages 249-266
    3. Douglas G. Walker, Lih-Fen Lue
      Pages 267-282
    4. Dave Morgan, Marcia N. Gordon
      Pages 283-293
    5. Paul L. Wood
      Pages 295-300
    6. G. Jean Harry, Christian Lefebvre d’Hellencourt
      Pages 301-329
    7. Patrick Pompl, Tara Brennan, Lap Ho, Giulio Maria Pasinetti
      Pages 331-342
  5. Multiple Sclerosis

    1. Front Matter
      Pages 343-343
    2. Hans-Peter Hartung, Bernd C. Kieseier
      Pages 345-357
    3. Claudia F. Lucchinetti, W. Brück, Hans Lassmann
      Pages 359-377
    4. Annachiara Cagnin, Alexander Gerhard, Richard B. Banati
      Pages 379-387
  6. Parkinson’s and Huntington’s Diseases

    1. Front Matter
      Pages 389-389
    2. Joseph Rogers, Carl J. Kovelowski
      Pages 391-403
  7. Back Matter
    Pages 417-419

About this book


The field of neuroinflammation is evolving rapidly and now yielding many new potential therapeutics for clinical trials. In this thoroughly updated and revised edition of his much praised book, Neuroinflammation: Mechanisms and Management, Second Edition, Paul L. Wood and a panel of leading researchers capture all these new developments in a masterful synthesis of what is known today about the inflammatory mediators and the cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.
Up-to-date and insightful, Neuroinflammation: Mechanisms and Management, Second Edition summarizes all the recent discoveries now playing a key role in both developing molecular targets and designing a new generation of drugs for acute and chronic neurodegenerative disorders alike.


Alzheimer Parkinson alzheimer's disease brain imaging techniques receptor spinal cord stroke

Editors and affiliations

  • Paul L. Wood
    • 1
  1. 1.Oxon MedicaSouth San FranciscoUSA

Bibliographic information

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