© 2002

Buprenorphine Therapy of Opiate Addiction

  • Pascal Kintz
  • Pierre Marquet

Part of the Forensic Science and Medicine book series (FSM)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Pierre Marquet
    Pages 1-11
  3. Michel Mallaret, Maurice Dematteis, Celine Villier, Claude Elisabeth Barjhoux, Chantal Gatignol
    Pages 51-67
  4. Marc Deveaux, Jean Vignau
    Pages 69-81
  5. Pascal Kintz
    Pages 109-117
  6. Pierre Marquet, Pierre Lavignasse, Jean-Michel Gaulier, Gérard Lachâtre
    Pages 125-135
  7. Claude Lejeune, Sandrine Aubisson, Laurence Simmat-Durand, Fabrice Cneude, Martine Piquet
    Pages 137-146
  8. Back Matter
    Pages 147-148

About this book


Buprenorphine, a semisynthetic opioid derivative, has been prescribed widely and uniquely in France as an alternative to methadone for the treatment of heroin-addicted patients during the last five years. In Buprenorphine Therapy of Opiate Addiction, participating physicians and toxicologists summarize and evaluate their experiences with this still uncommon drug, covering all aspects of its use, including the pharmacology, conditions of delivery, risks from use with other psychoactive drugs, toxicology and related deaths, as well as its testing in blood, urine, tissue, and hair. Special attention is given to comparing the long-term care of opiate-dependent patients using high-dose buprenorphine vs methadone, and to explaining the differences in treatment, administration, and delivery. The authors also describe how buprenorphine is currently prescribed and monitored in France and Australia, and review all the latest advances in analytical techniques for the determination of buprenorphine and its metabolites in biological fluids and tissues. Special coverage is given to the use of buprenorphine in the pregnant addict, the risks of buprenorphine overdosing and poisoning, and the effects of combining buprenorphine and naloxone.
Comprehensive and groundbreaking, Buprenorphine Therapy of Opiate Addiction covers all the key topics that both treatment personnel and forensic laboratory scientists in the addiction field need to appreciate the success of buprenorphine therapy, and to prepare for its implementation in their own countries.


Methadon pharmacodynamics pharmacokinetics pharmacology toxicology

Editors and affiliations

  • Pascal Kintz
    • 1
    • 2
  • Pierre Marquet
    • 3
    • 4
  1. 1.Institute of Legal MedicineStrasbourgFrance
  2. 2.Societé Française de Toxicologie AnalytiqueFrance
  3. 3.Department of Pharmacology and ToxicologyUniversity HospitalFrance
  4. 4.Faculty of MedicineLimoges UniversityLimogesFrance

Bibliographic information

  • Book Title Buprenorphine Therapy of Opiate Addiction
  • Editors Pascal Kintz
    Pierre Marquet
  • Series Title Forensic Science and Medicine
  • DOI
  • Copyright Information Humana Press 2002
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-1-58829-031-1
  • Softcover ISBN 978-1-4684-9713-7
  • eBook ISBN 978-1-59259-282-1
  • Edition Number 1
  • Number of Pages , 168
  • Number of Illustrations 22 b/w illustrations, 0 illustrations in colour
  • Topics Forensic Medicine
  • Buy this book on publisher's site
Industry Sectors


Foreword by Albert D. Fraser
"This is a very useful and timely book in addiction medicine. . .This book details the use of buprenorphine with its risks and benefits. It draws extensively from available studies and literature, which are listed very clearly in tables. Some of the appendixes are especially useful for quick references. This is a very useful and easy to read book. It details the use of buprenorphine therapy as an alternate to methadone treatment. It also details the analytical advances in testing for buprenorphines. The book describes buprenorphine's pharmacology and current prescription practices in France. It also discusses the use of buprenorphine in various scenarios including in pregnant addicts, and provides a source of knowledge for everyone working in addiction medicine."-Doody's Health Sciences Book Review Journal

"This is a further volume in the growing Forensic medicine and Science Series edited by Steve Karch. This impressive series embraces a range of forensic topics. The style is now familiar, good topic editors with a broad spectrum of specialist authors contributing within their own area of expertise...good topic editors with a broad spectrum of specialist authors contributing within their own area of expertise....worthwhile reading for anyone in contact with patients who are opiate addicted." - Nil Aggrawal's Internet Journal of Forensic Medicine and Toxicology