© 2003


Pathophysiology and Clinical Management

  • Eric S. Orwoll
  • Michael Bliziotes

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Robert F. Klein, Tatiana Foroud
    Pages 1-31
  3. Ego Seeman
    Pages 33-59
  4. Jean-Philippe Bonjour, René Rizzoli
    Pages 61-81
  5. Thomas F. Lang, Jeffrey Duryea
    Pages 83-104
  6. John Shepherd, Chris Njeh, Harry K. Genant
    Pages 105-119
  7. Berthold Fohr, Henning W. Woitge, Markus J. Seibel
    Pages 163-184
  8. Richard Eastell, Penny R. Bainbridge
    Pages 185-197
  9. Stefan Judex, Clinton Rubin
    Pages 199-220
  10. Christine M. Snow, Belinda R. Beck
    Pages 221-246
  11. Robert P. Heaney
    Pages 265-292
  12. Russell T. Turner, David Rickard, Thomas C. Spelsberg, Jean D. Sibonga
    Pages 309-329
  13. Kristine M. Wiren
    Pages 349-373
  14. Dirk Vanderschueren, Liesbeth Vandenput, Johannes V. Swinnen, Steven Boonen, Roger Bouillon
    Pages 375-391
  15. Benjamin Z. Leder, Joel S. Finkelstein
    Pages 393-411

About this book


With varying degrees of osteoporosis found in one of every four women older than 45 years of age and in nine out of ten women older than 75, as well as in men, osteoporosis is clearly a widespread disease with important health and economic impacts. It is also scientifically complex. In Osteoporosis: Pathophysiology and Clinical Management, leading clinicians and researchers join forces to illuminate in coupled chapters all the major scientific and clinical aspects of osteoporosis. By uniquely coupling basic and clinical chapters, the book illustrates the critical interdependence of investigators and practitioners. Traditional issues such as calcium supplementation and exercise are juxtaposed with state-of-the-art updates on molecular pharmacology and imaging. On the basic science side, topics range from the genetics of osteoporosis and bone turnover markers, to androgen action in bone, to the basic biology of estrogen and bone. On the clinical side the authors present the latest thinking about the use of bone densitometry in treatment, the use of vitamin D and its metabolites, and the clinical utilization of salmon calcitonin, as well as parathyroid and bisphosphonate therapies, SERMs, and other important treatments.
Unique in its integration of basic science and clinical practice, Osteoporosis: Pathophysiology and Clinical Management reveals the great progress that has occurred in the field, providing basic scientists with a clear view of the clinical state-of-the-art, and practicing physicians with a deeper understanding of the complex biology involved.


Vitamin D bone clinical trial fracture homeostasis hormone osteoporosis pathophysiology pharmacology physiology prevention steroid steroids thyroid hormone

Editors and affiliations

  • Eric S. Orwoll
    • 1
  • Michael Bliziotes
    • 1
  1. 1.Oregon Health & Science UniversityPortlandUSA

Bibliographic information

  • Book Title Osteoporosis
  • Book Subtitle Pathophysiology and Clinical Management
  • Editors Eric S. Orwoll
    Michael Bliziotes
  • Series Title Contemporary Endocrinology
  • DOI
  • Copyright Information Humana Press 2003
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-89603-933-9
  • Softcover ISBN 978-1-61737-260-5
  • eBook ISBN 978-1-59259-278-4
  • Edition Number 1
  • Number of Pages XI, 615
  • Number of Illustrations 53 b/w illustrations, 0 illustrations in colour
  • Topics Orthopedics
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals


"The editors present an exceptional book focused on pathophysiology as well as on the management of patients with osteoporosis." -European Radiology

"I recommend it because of its innovations and because it is packed with information." -New England Journal of Medicine