Immunotherapy for Infectious Diseases

  • Jeffrey M. Jacobson

Part of the Infectious Disease book series (ID)

Table of contents

  1. Front Matter
    Pages i-x
  2. Basic Principles of Immunity

    1. Front Matter
      Pages 1-1
    2. Peter L. Nara
      Pages 3-22
    3. Prosper N. Boyaka, Jerry R. McGhee
      Pages 39-60
  3. Molecular Basis for Immunotherapy

    1. Front Matter
      Pages 61-61
    2. Smriti K. Kundu-Raychaudhuri, Edgar G. Engleman
      Pages 99-116
    3. Constantin A. Bona
      Pages 129-147
  4. Immunotherapy for HIV Infection

    1. Front Matter
      Pages 149-149
    2. Lawrence M. Fox
      Pages 151-161
    3. Spyros A. Kalams
      Pages 181-197
    4. Jeffrey M. Jacobson
      Pages 199-220
    5. Ralph Dornburg, Roger J. Pomerantz
      Pages 237-248
  5. Immunotherapy for Infectious Diseases Other than HIV

    1. Front Matter
      Pages 249-249
    2. Michelle Onorato, Richard B. Pollard
      Pages 251-258
    3. Uluhan Sili, Helen Heslop, Cliona M. Rooney
      Pages 259-274
    4. Robert S. Wallis, John L. Johnson
      Pages 283-302
    5. Arturo Casadevall
      Pages 303-322
  6. Back Matter
    Pages 323-331

About this book


Because the search for safe and effective chemotherapeutic agents has been hindered by antimicrobial resistance and toxic harm, there is a growing need to understand how the immune system can be manipulated to control infections, particularly HIV. In Immunotherapy for Infectious Diseases, Jeffrey M. Jacobson, md, and a group of leading researchers active in the field review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by using chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function. Also discussed are immunotherapy for other viral infections, virus-associated malignancies, bacterial infections and sepsis, tuberculosis, and fungal infections.
Comprehensive and cutting-edge, Immunotherapy for Infectious Diseases reviews all the current state-of-the-art developments occurring in this rapidly evolving field and helps set the stage for the early development of better immunologically based therapies for infections.


Antigen HIV HIV infection Sepsis bacteria bacterial infection bacterial infections fungal infection gene therapy infection infections infectious infectious disease infectious diseases viral infection

Editors and affiliations

  • Jeffrey M. Jacobson
    • 1
  1. 1.AIDS CenterMount Sinai School of MedicineNew YorkUSA

Bibliographic information

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