© 2002


Basic Research and Clinical Applications

  • Jeffrey L. Platt

Table of contents

  1. Front Matter
    Pages i-x
  2. Matilde Bustos, Jeffrey L. Platt
    Pages 45-55
  3. Uri Galili
    Pages 57-71
  4. William Parker, Paul B. Yu, Yuko C. Nakamura
    Pages 73-85
  5. William Parker, Ryan C. Fields, Yuko C. Nakamura
    Pages 87-101
  6. Mauro S. Sandrin, Ian F. C. McKenzie
    Pages 119-137
  7. Agustin P. Dalmasso
    Pages 139-171
  8. Nicola Rogers, Robert Lechler
    Pages 173-197
  9. Antonello Pileggi, R. Damaris Molano, Thierry Berney, Luca Inverardi
    Pages 199-214
  10. Albert S. B. Edge
    Pages 247-263
  11. Back Matter
    Pages 265-270

About this book


Xenotransplantation might well provide a revolutionary way of augmenting the function of diseased tissues or replacing organs. This possibility has been advanced by newly acquired understanding of the biological and immunological obstacles to conducting transplantation between species. In Xenotransplantation: Basic Research and Clinical Applications, internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation and what impact these advances might optimally have on medicine and science. The authoritative experts writing here-many of whom made the basic discoveries underlying the recent advances-examine the biological and immunological hurdles to xenotransplantation, illuminating how the immune system interacts with the xenograft, and laying a practical foundation for the use of genetic engineering and animal transplants in the treatment of human disease.
Comprehensive and authoritative, Xenotransplantation: Basic Research and Clinical Applications provides basic and clinical investigators, as well as transplant surgeons, with today's most thorough and up-to-date compendium of vital information on all the scientific and technological aspects of xenotransplantation.


antibody antigen immune system immunity immunology transplantation

Editors and affiliations

  • Jeffrey L. Platt
    • 1
  1. 1.Transplantation Biology and the Departments of Surgery, Immunology, and PediatricsMayo ClinicRochesterUSA

Bibliographic information

  • Book Title Xenotransplantation
  • Book Subtitle Basic Research and Clinical Applications
  • Editors Jeffrey L. Platt
  • DOI
  • Copyright Information Humana Press 2002
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Hardcover ISBN 978-0-89603-674-1
  • Softcover ISBN 978-1-61737-127-1
  • eBook ISBN 978-1-59259-166-4
  • Edition Number 1
  • Number of Pages X, 270
  • Number of Illustrations 9 b/w illustrations, 0 illustrations in colour
  • Topics Transplant Surgery
    Theory of Medicine/Bioethics
  • Buy this book on publisher's site
Industry Sectors
Health & Hospitals
Surgery & Anesthesiology


"This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic" - Doody's Health Sciences Book Review Journal