Handbook of Neurotoxicology

Volume I

  • Edward J. Massaro

Table of contents

  1. Front Matter
    Pages i-xv
  2. Pesticides

    1. Front Matter
      Pages 1-1
    2. Anticholinesterase Insecticides

      1. Janice E. Chambers, Russell L. Carr
        Pages 3-16
      2. Marion Ehrich, Bernard S. Jortner
        Pages 17-27
    3. Pesticides that Target Ion Channels

      1. David M. Soderlund
        Pages 47-63
      2. Jeffrey R. Bloomquist
        Pages 65-77
      3. Larry P. Sheets
        Pages 79-87
    4. Miscellaneous Pesticides with Action on the Nervous System

      1. Dennis Blodgett, Marion Ehrich, Jeffrey R. Bloomquist
        Pages 91-103
  3. Metals

    1. Front Matter
      Pages 105-105
    2. Michelle K. Nihei, Tomás R. Guilarte
      Pages 107-133
    3. Nasser H. Zawia, Morad Razmiafshari
      Pages 135-160
    4. Michael Aschner, James R. Connor, David C. Dorman, Elise A. Malecki, Kent E. Vrana
      Pages 195-209
    5. Andrzej Szutowicz
      Pages 211-236
  4. Natural Toxins of Microbial Origin

    1. Front Matter
      Pages 237-237
    2. Lyndon E. Llewellyn
      Pages 239-256
    3. Neale R. Towers, Ian Garthwaite
      Pages 269-291
    4. Mark A. Poli, Frank J. Lebeda
      Pages 293-304
    5. Frédéric A. Meunier, Judit Herreros, Giampietro Schiavo, Bernard Poulain, Jordi Molgó
      Pages 305-347
    6. Lora E. Fleming, Lorraine Backer, Alan Rowan
      Pages 363-381
  5. Natural Toxins of Animal Origin

    1. Front Matter
      Pages 383-383
    2. J. Oliver Dolly, Giacinto Bagetta
      Pages 455-473
    3. Alfonso Grasso, Stefano Rufini
      Pages 475-501
    4. Marie-France Martin-Eauclaire
      Pages 503-528
    5. William R. Kem
      Pages 529-571
    6. William R. Kem
      Pages 573-593
    7. Frédéric A. Meunier, Gilles Ouanounou, Cesar Mattei, Pascal Chameau, Cesare Colasante, Yuri A. Ushkaryov et al.
      Pages 595-616
    8. Robert Newcomb, George Miljanich
      Pages 617-651
  6. Back Matter
    Pages 653-668

About this book


Neurotoxins-whether human-generated pollutants or natural products-have recently attracted growing scientific interest. In the Handbook of Neurotoxicology, Volumes I and II, many leading researchers and clinicians-all acknowledged experts-review in depth the status of research in key areas of current neurotoxicologic interest and examine the latest methodologies for in vivo assessment of a wide spectrum of agents exhibiting neurotoxicologic properties. This first volume of the Handbook focuses on the biological effects of human-made neurotoxins, as well as those of natural origin, which so often provide valuable therapeutics and research reagents. Topics range from anticholinesterase insecticides and pesticides that target ion channels, to such metals as mercury, lead, zinc, and to the polytypic byproducts of combustion and industrial manufacture. The natural toxins discussed include those of microbial origin (microbial, marine, clostridial, and botulilinal neurotoxins), as well as those of animal origin (snake, spider, and scorpion venoms). Volume II concentrates on the biological effects of human-made toxins on the developing nervous system, reviews the neuronal impact of drugs of abuse, and provides state-of-the-art methods for the evaluation of the biological effects of neurotoxicants by both imaging and neurobehavioral assessment. Up-to-date and timely, the Handbook of Neurotoxicology, Volumes I and II, not only affords today's biomedical and clinical investigators a full panoply of knowledge in all the critical areas of current neurotoxicologic interest, but also illuminates the latest methodologies for assessing the effects of a broad spectrum of significant neurotoxicological agents.


Nervous System drugs of abuse human-made toxin lead mercury neurobehavioral assessment neurotoxicity neurotoxicology pesticide zinc

Editors and affiliations

  • Edward J. Massaro
    • 1
  1. 1.The National Health and Environmental Effects Research LaboratoryDurhamUSA

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